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Innate barriers to viral infection.

Damania, B and Blackbourn, DJ (2012) Innate barriers to viral infection. Future Microbiol, 7 (7). pp. 815-822.

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Abstract

Innate immunity represents the foremost barrier to viral infection. In order to infect a cell efficiently, viruses need to evade innate immune effectors such as interferons and inflammatory cytokines. Pattern recognition receptors can detect viral components or pathogen-associated molecular patterns. These receptors then elicit innate immune responses that result in the generation of type I interferons and proinflammatory cytokines. Organized by the Society for General Microbiology, one session of this conference focused on the current state-of-the-art knowledge on innate barriers to infection of different RNA and DNA viruses. Experts working on innate immunity in the context of viral infection provided insight into different aspects of innate immune recognition and also discussed areas for future research. Here, we provide an overview of the session on innate barriers to infection.

Item Type: Article
Authors :
NameEmailORCID
Damania, BUNSPECIFIEDUNSPECIFIED
Blackbourn, DJd.blackbourn@surrey.ac.ukUNSPECIFIED
Date : July 2012
Identification Number : https://doi.org/10.2217/fmb.12.52
Uncontrolled Keywords : Cytokines, DNA Viruses, Humans, Immunity, Innate, Inflammation, Interferon Type I, RNA Viruses, Receptors, Pattern Recognition, Signal Transduction, Virus Diseases
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:51
Last Modified : 17 May 2017 14:45
URI: http://epubs.surrey.ac.uk/id/eprint/825419

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