University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Current statin treatment, DNA testing and cascade testing of UK patients with familial hypercholesterolaemia

Seed, M, Roughton, M, Pedersen, K, Nair, D, Wang, T, Neil, A and Humphries, S (2012) Current statin treatment, DNA testing and cascade testing of UK patients with familial hypercholesterolaemia Primary Care Cardiovascular Journal, 5 (4). pp. 181-185.

Full text not available from this repository.

Abstract

Familial hypercholesterolaemia (FH) is a monogenic inherited condition with high risk of premature CHD. We present the extent of LDL-C lowering, DNA testing and cascade testing in adults with FH attending UK lipid clinics. Only 44% of the patients achieved a >50% lowering of LDL-C from the baseline value. Half of all patients and 53% of women with CHD failed to achieve the target >50% reduction in LDL-C. There is a major lack of family "cascade" testing. Funding for DNA testing and cascade testing is lacking in many parts of the UK.

Item Type: Article
Authors :
NameEmailORCID
Seed, MUNSPECIFIEDUNSPECIFIED
Roughton, MUNSPECIFIEDUNSPECIFIED
Pedersen, KUNSPECIFIEDUNSPECIFIED
Nair, DUNSPECIFIEDUNSPECIFIED
Wang, Ttim.wang@surrey.ac.ukUNSPECIFIED
Neil, AUNSPECIFIEDUNSPECIFIED
Humphries, SUNSPECIFIEDUNSPECIFIED
Date : 1 October 2012
Identification Number : https://doi.org/10.3132/pccj.2012.050
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:49
Last Modified : 17 May 2017 14:45
URI: http://epubs.surrey.ac.uk/id/eprint/825274

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800