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Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

Richards, JB, Rivadeneira, F, Inouye, M, Pastinen, TM, Soranzo, N, Wilson, SG, Andrew, T, Falchi, M, Gwilliam, R, Ahmadi, KR , Valdes, AM, Arp, P, Whittaker, P, Verlaan, DJ, Jhamai, M, Kumanduri, V, Moorhouse, M, van Meurs, JB, Hofman, A, Pols, HA, Hart, D, Zhai, G, Kato, BS, Mullin, BH, Zhang, F, Deloukas, P, Uitterlinden, AG and Spector, TD (2008) Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Lancet, 371 (9623). pp. 1505-1512.

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Abstract

Osteoporosis is diagnosed by the measurement of bone mineral density, which is a highly heritable and multifactorial trait. We aimed to identify genetic loci that are associated with bone mineral density.

Item Type: Article
Authors :
NameEmailORCID
Richards, JBUNSPECIFIEDUNSPECIFIED
Rivadeneira, FUNSPECIFIEDUNSPECIFIED
Inouye, MUNSPECIFIEDUNSPECIFIED
Pastinen, TMUNSPECIFIEDUNSPECIFIED
Soranzo, NUNSPECIFIEDUNSPECIFIED
Wilson, SGUNSPECIFIEDUNSPECIFIED
Andrew, TUNSPECIFIEDUNSPECIFIED
Falchi, MUNSPECIFIEDUNSPECIFIED
Gwilliam, RUNSPECIFIEDUNSPECIFIED
Ahmadi, KRk.ahmadi@surrey.ac.ukUNSPECIFIED
Valdes, AMUNSPECIFIEDUNSPECIFIED
Arp, PUNSPECIFIEDUNSPECIFIED
Whittaker, PUNSPECIFIEDUNSPECIFIED
Verlaan, DJUNSPECIFIEDUNSPECIFIED
Jhamai, MUNSPECIFIEDUNSPECIFIED
Kumanduri, VUNSPECIFIEDUNSPECIFIED
Moorhouse, MUNSPECIFIEDUNSPECIFIED
van Meurs, JBUNSPECIFIEDUNSPECIFIED
Hofman, AUNSPECIFIEDUNSPECIFIED
Pols, HAUNSPECIFIEDUNSPECIFIED
Hart, DUNSPECIFIEDUNSPECIFIED
Zhai, GUNSPECIFIEDUNSPECIFIED
Kato, BSUNSPECIFIEDUNSPECIFIED
Mullin, BHUNSPECIFIEDUNSPECIFIED
Zhang, FUNSPECIFIEDUNSPECIFIED
Deloukas, PUNSPECIFIEDUNSPECIFIED
Uitterlinden, AGUNSPECIFIEDUNSPECIFIED
Spector, TDUNSPECIFIEDUNSPECIFIED
Date : 3 May 2008
Identification Number : 10.1016/S0140-6736(08)60599-1
Uncontrolled Keywords : Alleles, Bone Density, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 8, Female, Fractures, Bone, Gene Expression, Genetic Markers, Genome, Human, Genotype, Humans, LDL-Receptor Related Proteins, Low Density Lipoprotein Receptor-Related Protein-5, Lumbar Vertebrae, Male, Middle Aged, Osteoporosis, Osteoprotegerin, Polymorphism, Single Nucleotide
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:48
Last Modified : 17 May 2017 14:45
URI: http://epubs.surrey.ac.uk/id/eprint/825188

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