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The basis of differential responses to folic acid supplementation.

Cotlarciuc, I, Andrew, T, Dew, T, Clement, G, Gill, R, Surdulescu, G, Sherwood, R and Ahmadi, KR (2011) The basis of differential responses to folic acid supplementation. J Nutrigenet Nutrigenomics, 4 (2). pp. 99-109.

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Abstract

Elevated levels of total homocysteine (tHcy) are associated with an increased risk of many common diseases. Supplementation with folic acid has been shown to significantly reduce tHcy levels. We used the classical twin model to partition the variability in changes in plasma tHcy levels through folic acid supplementation into genetic, environmental, and confounding epidemiological factors.

Item Type: Article
Authors :
NameEmailORCID
Cotlarciuc, IUNSPECIFIEDUNSPECIFIED
Andrew, TUNSPECIFIEDUNSPECIFIED
Dew, TUNSPECIFIEDUNSPECIFIED
Clement, GUNSPECIFIEDUNSPECIFIED
Gill, RUNSPECIFIEDUNSPECIFIED
Surdulescu, GUNSPECIFIEDUNSPECIFIED
Sherwood, RUNSPECIFIEDUNSPECIFIED
Ahmadi, KRk.ahmadi@surrey.ac.ukUNSPECIFIED
Date : 2011
Identification Number : 10.1159/000327768
Uncontrolled Keywords : Aged, Aged, 80 and over, Female, Folic Acid, Genetic Predisposition to Disease, Homocysteine, Humans, Hyperhomocysteinemia, Methylenetetrahydrofolate Reductase (NADPH2), Middle Aged, Models, Genetic, Nutrigenomics, Polymorphism, Single Nucleotide, Twins, Dizygotic, Twins, Monozygotic, Vitamin B 12
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:48
Last Modified : 17 May 2017 14:45
URI: http://epubs.surrey.ac.uk/id/eprint/825178

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