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Evaluation of Viburnum foetens for anticancer and antibacterial potential and phytochemical analysis

Bibi, Y, Nisa, S, Sarwar, S, Chaudhary, MA, Waheed, A, Zia, M and Ahmed, S (2010) Evaluation of Viburnum foetens for anticancer and antibacterial potential and phytochemical analysis African Journal of Biotechnology, 9 (34). pp. 5611-5615.

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Abstract

Viburnum foetens is an ethanobotanically important plant species traditionally used as purgative and also have sedative properties. Methanol extract from leaf explants was used to determine cytotoxic and antibacterial potential of this potent shrub. It was observed that cytotoxicity against MCF-7 cell lines gradually increases according to concentration of extract used. Further, the methanol crude extract was fractionated on polarity basis and each fraction was again tested for cytotoxic potential. Methanol fraction showed 83% inhibition that was highest from all other fractions. The crude methanol extract showed mild activity ranging from 10.30 to 12.00 mm zones of inhibition against bacterial strains tested by agar well diffusion method. Phytochemical analysis reveals that methanol fraction contain flavonoids, coumarins and tannins only, while crude extract include other phytochemicals along with these. It can be suggested that V. foetens contains some anticancerous compounds to be isolated and can be used as drug.

Item Type: Article
Authors :
NameEmailORCID
Bibi, YUNSPECIFIEDUNSPECIFIED
Nisa, SUNSPECIFIEDUNSPECIFIED
Sarwar, SUNSPECIFIEDUNSPECIFIED
Chaudhary, MAUNSPECIFIEDUNSPECIFIED
Waheed, Aa.waheed@surrey.ac.ukUNSPECIFIED
Zia, MUNSPECIFIEDUNSPECIFIED
Ahmed, SUNSPECIFIEDUNSPECIFIED
Date : 2010
Identification Number : 10.5897/AJB09.1867
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:47
Last Modified : 17 May 2017 14:44
URI: http://epubs.surrey.ac.uk/id/eprint/825154

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