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Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs

Hu, L, Wu, X, Han, J, Chen, L, Vass, SO, Browne, P, Hall, BS, Bot, C, Gobalakrishnapillai, V, Searle, PF , Knox, RJ and Wilkinson, SR (2011) Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21 (13). pp. 3986-3991.

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Item Type: Article
Authors :
NameEmailORCID
Hu, LUNSPECIFIEDUNSPECIFIED
Wu, XUNSPECIFIEDUNSPECIFIED
Han, JUNSPECIFIEDUNSPECIFIED
Chen, LUNSPECIFIEDUNSPECIFIED
Vass, SOUNSPECIFIEDUNSPECIFIED
Browne, PUNSPECIFIEDUNSPECIFIED
Hall, BSb.s.hall@surrey.ac.ukUNSPECIFIED
Bot, CUNSPECIFIEDUNSPECIFIED
Gobalakrishnapillai, VUNSPECIFIEDUNSPECIFIED
Searle, PFUNSPECIFIEDUNSPECIFIED
Knox, RJUNSPECIFIEDUNSPECIFIED
Wilkinson, SRUNSPECIFIEDUNSPECIFIED
Date : 1 July 2011
Identification Number : 10.1016/j.bmcl.2011.05.009
Uncontrolled Keywords : Science & Technology, Life Sciences & Biomedicine, Physical Sciences, Chemistry, Medicinal, Chemistry, Organic, Pharmacology & Pharmacy, Chemistry, CHEMISTRY, MEDICINAL, CHEMISTRY, ORGANIC, Nitroreductase, Prodrug, Phosphoramide mustard, Antiproliferative, Trypanosoma, Leishmania, ANTIBODY-DIRECTED ENZYME, DRUG-DELIVERY, THERAPY, DESIGN, STRATEGIES, RESISTANCE, HYPOXIA, AGENTS
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:43
Last Modified : 17 May 2017 14:44
URI: http://epubs.surrey.ac.uk/id/eprint/824820

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