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Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.

McGee, KC, Shahmanesh, M, Boothby, M, Nightingale, P, Gathercole, LL, Tripathi, G, Harte, AL, Shojaee-Moradie, F, Umpleby, AM, Das, S , Al-Daghri, NM, McTernan, PG and Tomlinson, JW (2012) Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones. Antivir Ther, 17 (3). pp. 495-507.

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Abstract

Antiretroviral (ARV) treatment has been associated with abnormalities in lipid and mitochondrial metabolism. We compared patterns of gene expression in the subcutaneous adipose tissue (SAT) of HIV-positive subjects before and after 18-24 months of ARV therapy with HIV-negative controls.

Item Type: Article
Authors :
NameEmailORCID
McGee, KCUNSPECIFIEDUNSPECIFIED
Shahmanesh, MUNSPECIFIEDUNSPECIFIED
Boothby, MUNSPECIFIEDUNSPECIFIED
Nightingale, PUNSPECIFIEDUNSPECIFIED
Gathercole, LLUNSPECIFIEDUNSPECIFIED
Tripathi, GUNSPECIFIEDUNSPECIFIED
Harte, ALUNSPECIFIEDUNSPECIFIED
Shojaee-Moradie, Ff.shojaee-moradie@surrey.ac.ukUNSPECIFIED
Umpleby, AMUNSPECIFIEDUNSPECIFIED
Das, SUNSPECIFIEDUNSPECIFIED
Al-Daghri, NMUNSPECIFIEDUNSPECIFIED
McTernan, PGUNSPECIFIEDUNSPECIFIED
Tomlinson, JWUNSPECIFIEDUNSPECIFIED
Date : 2012
Identification Number : 10.3851/IMP2017
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:41
Last Modified : 17 May 2017 09:41
URI: http://epubs.surrey.ac.uk/id/eprint/824706

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