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Recent Clinical Experience With Oncolytic Viruses.

Donnelly, OG, Errington-Mais, F, Prestwich, R, Harrington, K, Pandha, H, Vile, R and Melcher, AA (2011) Recent Clinical Experience With Oncolytic Viruses. Curr Pharm Biotechnol.

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Abstract

There has been interest in using viruses to treat cancer for over a century. Recent clinical efforts, driven on by significant preclinical advances, have focussed on the safety of using replication-competent viruses. Recently published clinical trials of six oncolytic viruses (adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus and vaccinia) have added to the accumulating data that endorse oncolytic viruses as a safe and well tolerated treatment approach. Conclusive evidence of efficacy remains to be demonstrated, but randomised clinical trials are now underway.

Item Type: Article
Authors :
NameEmailORCID
Donnelly, OGUNSPECIFIEDUNSPECIFIED
Errington-Mais, FUNSPECIFIEDUNSPECIFIED
Prestwich, RUNSPECIFIEDUNSPECIFIED
Harrington, KUNSPECIFIEDUNSPECIFIED
Pandha, Hh.pandha@surrey.ac.ukUNSPECIFIED
Vile, RUNSPECIFIEDUNSPECIFIED
Melcher, AAUNSPECIFIEDUNSPECIFIED
Date : 8 July 2011
Identification Number : https://doi.org/10.2174/138920112800958904
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:33
Last Modified : 17 May 2017 14:43
URI: http://epubs.surrey.ac.uk/id/eprint/824191

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