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Differential effects of insulin detemir and neutral protamine Hagedorn (NPH) insulin on hepatic glucose production and peripheral glucose uptake during hypoglycaemia in type 1 diabetes.

Smeeton, F, Shojaee Moradie, F, Jones, RH, Westergaard, L, Haahr, H, Umpleby, AM and Russell-Jones, DL (2009) Differential effects of insulin detemir and neutral protamine Hagedorn (NPH) insulin on hepatic glucose production and peripheral glucose uptake during hypoglycaemia in type 1 diabetes. Diabetologia, 52 (11). pp. 2317-2323.

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Abstract

We compared the symptoms of hypoglycaemia induced by insulin detemir (NN304) (B29Lys(epsilon-tetradecanoyl),desB30 human insulin) and equally effective doses of neutral protamine Hagedorn (NPH) insulin in relation to possible differential effects on hepatic glucose production and peripheral glucose uptake.

Item Type: Article
Authors :
NameEmailORCID
Smeeton, FUNSPECIFIEDUNSPECIFIED
Shojaee Moradie, FUNSPECIFIEDUNSPECIFIED
Jones, RHUNSPECIFIEDUNSPECIFIED
Westergaard, LUNSPECIFIEDUNSPECIFIED
Haahr, HUNSPECIFIEDUNSPECIFIED
Umpleby, AMUNSPECIFIEDUNSPECIFIED
Russell-Jones, DLdavidrussell-jones@nhs.netUNSPECIFIED
Date : November 2009
Identification Number : 10.1007/s00125-009-1487-4
Uncontrolled Keywords : Blood Glucose, Blood Pressure, Cross-Over Studies, Diabetes Mellitus, Type 1, Double-Blind Method, Epinephrine, Glucose, Growth Hormone, Heart Rate, Humans, Hypoglycemia, Hypoglycemic Agents, Infusions, Intravenous, Insulin, Insulin, Isophane, Insulin, Long-Acting, Liver, Patient Selection, Reaction Time
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:01
Last Modified : 17 May 2017 09:01
URI: http://epubs.surrey.ac.uk/id/eprint/821931

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