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Safety of Measles-Containing Vaccines in Post-Marketing Surveillance in Anhui, China

Meng, F-Y, Sun, Y, Shen, Y-G, Pan, H-F, Tang, J-H, Wang, B-B, Wu, Changhao and Ye, D-Q (2017) Safety of Measles-Containing Vaccines in Post-Marketing Surveillance in Anhui, China PLoS One, 12 (2), e0172108.

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Abstract

The safety of measles vaccination is of great interest to public health practice and the general society. We have analyzed the adverse events following immunization (AEFI) of currently used measles-containing vaccines (including live attenuated measles vaccine, live attenuated measles and rubella combined vaccine, live attenuated measles and mumps combined vaccine, live attenuated Measles, Mumps and Rubella Combined Vaccine) in Anhui Province, China. From 2009 to 2014, 9.9 million doses of measles-containing vaccines were administrated and 1893 AEFIs were found (191.4 per million doses), of which, 33 serious adverse events (3.3 per million vaccine doses) were reported. 59.4% (1124 cases) were male cases, and 85.1% (1611 cases) occurred in persons aged < 1 year. 93.3% (1766 cases) occurred at the first dose of vaccination and 95.9% (1815 cases) were found within 3 days after vaccination. This study presents up-to-date data and suggests that the measles-containing vaccines used in Anhui Province of China are safe.

Item Type: Article
Subjects : Biosciences and Medicine
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Meng, F-YUNSPECIFIEDUNSPECIFIED
Sun, YUNSPECIFIEDUNSPECIFIED
Shen, Y-GUNSPECIFIEDUNSPECIFIED
Pan, H-FUNSPECIFIEDUNSPECIFIED
Tang, J-HUNSPECIFIEDUNSPECIFIED
Wang, B-BUNSPECIFIEDUNSPECIFIED
Wu, ChanghaoC.Wu@surrey.ac.ukUNSPECIFIED
Ye, D-QUNSPECIFIEDUNSPECIFIED
Date : 13 February 2017
Identification Number : 10.1371/journal.pone.0172108
Copyright Disclaimer : © 2017 Meng et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 10 Feb 2017 10:48
Last Modified : 07 Jul 2017 08:51
URI: http://epubs.surrey.ac.uk/id/eprint/813507

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