University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Functional imaging and texture analysis in radiotherapy planning.

Alobaidli, Sheaka (2017) Functional imaging and texture analysis in radiotherapy planning. Doctoral thesis, University of Surrey.

[img] Text (thesis)
thesis_Final.pdf - Version of Record
Restricted to Repository staff only until 31 January 2018.
Available under License Creative Commons Attribution Non-commercial Share Alike.

Download (18MB)
[img] Text (embargo document)
thesis_restrict2.pdf
Restricted to Repository staff only
Available under License Creative Commons Attribution Non-commercial Share Alike.

Download (622kB)

Abstract

In this thesis, a methodology is developed to generate optimised three-dimensional voxel-based CT texture maps (3D-VTM) to examine regional heterogeneity information within tumours and their relation to tumour metabolism measured as 18F-fluoro-deoxy glucose (18F-FDG) Positron Emission Tomography (PET) distributions. Ten patients diagnosed with advanced non-small cell lung cancer (NSCLC) were investigated. For optimal texture information decoding, an optimised quantisation method is presented. The texture feature that reflects heterogeneity and which showed correlation with patients’ survival was chosen for this thesis. To account for respiratory motion effects, an in-house designed phantom was used to characterise the effects of motion on texture analysis and consequently adapt our method in that regard.

Item Type: Thesis (Doctoral)
Subjects : Texture analysis, Radiotherapy, functional imaging
Divisions : Theses
Authors :
NameEmailORCID
Alobaidli, Sheakasheakaa@gmail.comUNSPECIFIED
Date : 31 January 2017
Funders : The Kuwaiti Goverment
Contributors :
ContributionNameEmailORCID
http://www.loc.gov/loc.terms/relators/THSEvans, Philp.evans@surrey.ac.ukUNSPECIFIED
Depositing User : Sheaka Alobaidli
Date Deposited : 06 Feb 2017 12:19
Last Modified : 17 May 2017 14:26
URI: http://epubs.surrey.ac.uk/id/eprint/813156

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800