University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Amerindian (but not African or European) ancestry is significantly associated with diurnal preference within an admixed Brazilian population

Egan, Kieren, Campos Santos, H, Beijamini, F, Duarte, NE, Horimoto, ARVR, Taporoski, TP, Vallada, H, Negrão, AB, Krieger, JE, Pedrazzoli, M , Knutson, KL, Pereira, AC and von Schantz, Malcolm (2017) Amerindian (but not African or European) ancestry is significantly associated with diurnal preference within an admixed Brazilian population Chronobiology International: the journal of biological and medical rhythm research, 34 (2). pp. 269-272.

[img] Text
amerindian paper.pdf - Accepted version Manuscript
Restricted to Repository staff only until 5 January 2018.
Available under License : See the attached licence file.

Download (518kB)
[img]
Preview
Text (licence)
SRI_deposit_agreement.pdf
Available under License : See the attached licence file.

Download (33kB) | Preview

Abstract

Significant questions remain unanswered regarding the genetic versus environmental contributions to racial/ethnic differences in sleep and circadian rhythms. We addressed this question by investigating the association between diurnal preference, using the Morningness-Eveningness questionnaire (MEQ), and genetic ancestry within the Baependi Heart Study cohort, a highly admixed Brazilian population based in a rural town. Analysis was performed using measures of ancestry, using the Admixture program, and MEQ from 1,453 individuals. We found an association between the degree of Amerindian (but not European of African) ancestry and morningness, equating to 0.16 units for each additional percent of Amerindian ancestry, after adjustment for age, sex, education, and residential zone. To our knowledge, this is the first published report identifying an association between genetic ancestry and MEQ, and above all, the first one based on ancestral contributions within individuals living in the same community. This previously unknown ancestral dimension of diurnal preference suggests a stratification between racial/ethnic groups in an as yet unknown number of genetic polymorphisms.

Item Type: Article
Subjects : Biosciences and Medicine
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Egan, Kierenk.egan@surrey.ac.ukUNSPECIFIED
Campos Santos, HUNSPECIFIEDUNSPECIFIED
Beijamini, FUNSPECIFIEDUNSPECIFIED
Duarte, NEUNSPECIFIEDUNSPECIFIED
Horimoto, ARVRUNSPECIFIEDUNSPECIFIED
Taporoski, TPUNSPECIFIEDUNSPECIFIED
Vallada, HUNSPECIFIEDUNSPECIFIED
Negrão, ABUNSPECIFIEDUNSPECIFIED
Krieger, JEUNSPECIFIEDUNSPECIFIED
Pedrazzoli, MUNSPECIFIEDUNSPECIFIED
Knutson, KLUNSPECIFIEDUNSPECIFIED
Pereira, ACUNSPECIFIEDUNSPECIFIED
von Schantz, MalcolmM.Von.Schantz@surrey.ac.ukUNSPECIFIED
Date : 5 January 2017
Identification Number : 10.1080/07420528.2016.1265979
Copyright Disclaimer : This is an Accepted Manuscript of an article published by Taylor & Francis in Chronobiology International on 5 January 2017, available online: http://www.tandfonline.com/10.1080/07420528.2016.1265979
Uncontrolled Keywords : Admixture; American Native Continental Ancestry Group; Brazil; Chronotype; Circadian rhythm; Diurnal preference; Sleep homeostasis
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 24 Nov 2016 13:12
Last Modified : 07 Jul 2017 11:55
URI: http://epubs.surrey.ac.uk/id/eprint/812953

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800