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NMR-based metabolic characterization of chicken tissues and biofluids: a model for avian research

Le Roy, CI, Mappley, LJ, La Ragione, Roberto, Woodward, MJ and Claus, SP (2016) NMR-based metabolic characterization of chicken tissues and biofluids: a model for avian research Metabolomics, 12, 157.

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Abstract

Introduction Poultry is one of the most consumed meat in the world and its related industry is always looking for ways to improve animal welfare and productivity. It is therefore essential to understand the metabolic response of the chicken to new feed formulas, various supplements, infections and treatments. Objectives As a basis for future research investigating the impact of diet and infections on chicken’s metabolism, we established a high-resolution proton nuclear magnetic resonance (NMR)-based metabolic atlas of the healthy chicken (Gallus gallus). Methods Metabolic extractions were performed prior to 1 H-NMR and 2D NMR spectra acquisition on twelve biological matrices: liver, kidney, spleen, plasma, egg yolk and white, colon, caecum, faecal water, ileum, pectoral muscle and brain of 6 chickens. Metabolic profiles were then exhaustively characterized. Results Nearly 80 metabolites were identified. A crosscomparison of these matrices was performed to determine metabolic variations between and within each section and highlighted that only eight core metabolites were systematically found in every matrice. Conclusion This work constitutes a database for future NMR-based metabolomic investigations in relation to avian production and health.

Item Type: Article
Subjects : Veterinary Medicine
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
NameEmailORCID
Le Roy, CIUNSPECIFIEDUNSPECIFIED
Mappley, LJUNSPECIFIEDUNSPECIFIED
La Ragione, RobertoR.Laragione@surrey.ac.ukUNSPECIFIED
Woodward, MJUNSPECIFIEDUNSPECIFIED
Claus, SPUNSPECIFIEDUNSPECIFIED
Date : 15 September 2016
Identification Number : 10.1007/s11306-016-1105-7
Copyright Disclaimer : Copyright The Author(s) 2016. This article is published with open access at Springerlink.com
Uncontrolled Keywords : s Chicken Metabolome Nuclear magnetic resonance spectroscopy (NMR) Metabolite
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 16 Sep 2016 15:59
Last Modified : 08 Aug 2017 08:21
URI: http://epubs.surrey.ac.uk/id/eprint/812214

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