University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Diagnosing Paroxysmal Atrial Fibrillation: Are Biomarkers the Solution to This Elusive Arrhythmia?

Howlett, PJ, Hatch, FS, Alexeenko, V, Jabr, RI, Leatham, EW and Fry, CH (2015) Diagnosing Paroxysmal Atrial Fibrillation: Are Biomarkers the Solution to This Elusive Arrhythmia? BioMed Research International, 2015, 910267.

[img]
Preview
Text
Diagnosing Paroxysmal Atrial Fibrillation - Are Biomarkers the Solution to This Elusive Arrhythmia.pdf - Version of Record
Available under License : See the attached licence file.

Download (1MB) | Preview
[img]
Preview
Text (licence)
SRI_deposit_agreement.pdf
Available under License : See the attached licence file.

Download (33kB) | Preview

Abstract

Atrial fibrillation (AF) is the commonest sustained arrhythmia globally and results in significantly increased morbidity and mortality including a fivefold risk of stroke. Paroxysmal atrial fibrillation (PAF) constitutes approximately half of all AF cases and is thought to represent an early stage of the disease. This intermittent form of atrial arrhythmia can be a challenge to identify and as a result many affected individuals are not prescribed appropriate antithrombotic therapy and hence are at risk of stroke and thromboembolism. Despite these adverse outcomes there have been relatively few diagnostic advances in the field since the introduction of the Holter monitor in 1949. This review aims to establish the available evidence for electrophysiological, molecular, and morphological biomarkers to improve the detection of PAF with reference to the underlying mechanisms for the condition.

Item Type: Article
Subjects : Medical Science
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Howlett, PJUNSPECIFIEDUNSPECIFIED
Hatch, FSUNSPECIFIEDUNSPECIFIED
Alexeenko, VUNSPECIFIEDUNSPECIFIED
Jabr, RIUNSPECIFIEDUNSPECIFIED
Leatham, EWUNSPECIFIEDUNSPECIFIED
Fry, CHUNSPECIFIEDUNSPECIFIED
Date : 2015
Identification Number : 10.1155/2015/910267
Copyright Disclaimer : Copyright © 2015 P. J. Howlett et al. This is an open access article made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords : Atrial Fibrillation, Biomarkers, Humans
Depositing User : Symplectic Elements
Date Deposited : 13 Sep 2016 15:11
Last Modified : 31 Oct 2017 18:42
URI: http://epubs.surrey.ac.uk/id/eprint/812152

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800