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Insulin-like growth factor binding protein-1 in insulin resistance and cardiovascular disease

Mehta, S, Livingstone, C, Borai, A and Ferns, G (2012) Insulin-like growth factor binding protein-1 in insulin resistance and cardiovascular disease British Journal of Diabetes and Vascular Disease, 12 (1). pp. 17-25.

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Abstract

Insulin-like growth factors (IGFs) are peptide hormones that have significant structural homology with insulin. IGF binding proteins (IGFBPs), in particular IGFBP-1, are important determinants of IGF activity such as enhancing peripheral glucose uptake, decreasing hepatic glucose output and modifying lipid metabolism. Herein factors which alter IGFBP-1 and the utility of measuring IGFBP-1 are considered as the role of IGFBP-1 is explored within the context of insulin resistance and the development of cardiovascular disease. © SAGE Publications 2012.

Item Type: Article
Subjects : Medical Science
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
AuthorsEmailORCID
Mehta, SUNSPECIFIEDUNSPECIFIED
Livingstone, CUNSPECIFIEDUNSPECIFIED
Borai, AUNSPECIFIEDUNSPECIFIED
Ferns, GUNSPECIFIEDUNSPECIFIED
Date : 1 January 2012
Identification Number : 10.1177/1474651412436701
Copyright Disclaimer : © The Author(s), 2012 Reprints and permissions: http://www.sagepub.co.uk/journalsPermissions.nav
Depositing User : Symplectic Elements
Date Deposited : 01 Sep 2016 11:55
Last Modified : 01 Sep 2016 11:55
URI: http://epubs.surrey.ac.uk/id/eprint/811952

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