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The insulin-like growth factor system and nutritional assessment.

Livingstone, C (2012) The insulin-like growth factor system and nutritional assessment. Scientifica, 2012. p. 768731.

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Over recent years there has been considerable interest in the role of the insulin-like growth factor (IGF) system in health and disease. It has long been known to be dysregulated in states of under- and overnutrition, serum IGF-I levels falling in malnourished patients and responding promptly to nutritional support. More recently, other proteins in this system have been observed to be dysregulated in both malnutrition and obesity. Currently no biochemical marker is sufficiently specific for use in screening for malnutrition, but levels may be valuable in providing information on nutritional status and in monitoring of nutritional support. All have limitations as nutritional markers in that their serum levels are influenced by factors other than nutritional status, most importantly the acute phase response (APR). Levels should be interpreted along with clinical findings and the results of other investigations such as C-reactive protein (CRP). This paper reviews data supporting the use of proteins of the IGF system as nutritional markers.

Item Type: Article
Subjects : Medical Science
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Date : 2012
Identification Number : 10.6064/2012/768731
Copyright Disclaimer : Copyright © 2012 Callum Livingstone. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 01 Sep 2016 11:32
Last Modified : 01 Sep 2016 11:32

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