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Assessment of Diet and Physical Activity in Paediatric Non-Alcoholic Fatty Liver Disease Patients: A United Kingdom Case Control Study

Gibson, PS, Lang, S, Gilbert, M, Kamat, D, Bansal, S, Ford-Adams, ME, Desai, AP, Dhawan, A, Fitzpatrick, E, Moore, JB and Hart, KH (2015) Assessment of Diet and Physical Activity in Paediatric Non-Alcoholic Fatty Liver Disease Patients: A United Kingdom Case Control Study NUTRIENTS, 7 (12). pp. 9721-9733.

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Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in children, with prevalence rising alongside childhood obesity rates. This study aimed to characterise the habitual diet and activity behaviours of children with NAFLD compared to obese children without liver disease in the United Kingdom (UK). Twenty-four biopsy-proven paediatric NAFLD cases and eight obese controls without biochemical or radiological evidence of NAFLD completed a 24-h dietary recall, a Physical Activity Questionnaire (PAQ), a Dutch Eating Behavior Questionnaire (DEBQ) and a 7-day food and activity diary (FAD), in conjunction with wearing a pedometer. Groups were well matched for age and gender. Obese children had higher BMI z-scores (p = 0.006) and BMI centiles (p = 0.002) than participants with NAFLD. After adjusting for multiple hypotheses testing and controlling for differences in BMI, no differences in macro- or micronutrient intake were observed as assessed using either 24-h recall or 7-day FAD (p > 0.001). Under-reporting was prevalent (NAFLD 75%, Obese Control 87%: p = 0.15). Restrained eating behaviours were significantly higher in the NAFLD group (p = 0.005), who also recorded more steps per day than the obese controls (p = 0.01). In conclusion, this is the first study to assess dietary and activity patterns in a UK paediatric NAFLD population. Only a minority of cases and controls were meeting current dietary and physical activity recommendations. Our findings do not support development of specific dietary/ physical activity guidelines for children with NAFLD; promoting adherence with current general paediatric recommendations for health should remain the focus of clinical management.

Item Type: Article
Subjects : Nutrition
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Nutritional Sciences
Authors :
AuthorsEmailORCID
Gibson, PSUNSPECIFIEDUNSPECIFIED
Lang, SUNSPECIFIEDUNSPECIFIED
Gilbert, MUNSPECIFIEDUNSPECIFIED
Kamat, DUNSPECIFIEDUNSPECIFIED
Bansal, SUNSPECIFIEDUNSPECIFIED
Ford-Adams, MEUNSPECIFIEDUNSPECIFIED
Desai, APUNSPECIFIEDUNSPECIFIED
Dhawan, AUNSPECIFIEDUNSPECIFIED
Fitzpatrick, EUNSPECIFIEDUNSPECIFIED
Moore, JBUNSPECIFIEDUNSPECIFIED
Hart, KHUNSPECIFIEDUNSPECIFIED
Date : 1 December 2015
Identification Number : 10.3390/nu7125494
Copyright Disclaimer : © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
Uncontrolled Keywords : Science & Technology, Life Sciences & Biomedicine, Nutrition & Dietetics, non-alcoholic fatty liver disease, nutrition, obesity, physical activity, eating behaviour, adolescence, children, HEPATIC STEATOSIS, FRUCTOSE CONSUMPTION, VITAMIN-D, CHILDREN, ADOLESCENTS, POPULATION, NAFLD, STEATOHEPATITIS, METAANALYSIS, PREVALENCE
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 06 Sep 2016 16:33
Last Modified : 06 Sep 2016 16:33
URI: http://epubs.surrey.ac.uk/id/eprint/811875

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