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Diagnosis of tuberculosis in groups of badgers: an exploration of the impact of trapping efficiency, infection prevalence and the use of multiple tests.

Buzdugan, SN, Chambers, MA, Delahay, RJ and Drewe, JA (2016) Diagnosis of tuberculosis in groups of badgers: an exploration of the impact of trapping efficiency, infection prevalence and the use of multiple tests. Epidemiology and Infection, 144 (8). pp. 1717-1727.

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Abstract

Accurate detection of infection with Mycobacterium bovis in live badgers would enable targeted tuberculosis control. Practical challenges in sampling wild badger populations mean that diagnosis of infection at the group (rather than the individual) level is attractive. We modelled data spanning 7 years containing over 2000 sampling events from a population of wild badgers in southwest England to quantify the ability to correctly identify the infection status of badgers at the group level. We explored the effects of variations in: (1) trapping efficiency; (2) prevalence of M. bovis; (3) using three diagnostic tests singly and in combination with one another; and (4) the number of badgers required to test positive in order to classify groups as infected. No single test was able to reliably identify infected badger groups if 80% sensitive, at least 94% specific, and able to be performed rapidly in the field.

Item Type: Article
Subjects : Veterinary Medicine
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
AuthorsEmailORCID
Buzdugan, SNUNSPECIFIEDUNSPECIFIED
Chambers, MAUNSPECIFIEDUNSPECIFIED
Delahay, RJUNSPECIFIEDUNSPECIFIED
Drewe, JAUNSPECIFIEDUNSPECIFIED
Date : June 2016
Identification Number : 10.1017/S0950268815003210
Copyright Disclaimer : © Crown Copyright. Published by Cambridge University Press 2016
Uncontrolled Keywords : Diagnosis, Disease control, Epidemiology, Tuberculosis (TB), Wildlife
Depositing User : Symplectic Elements
Date Deposited : 27 Jul 2016 13:31
Last Modified : 27 Jul 2016 13:31
URI: http://epubs.surrey.ac.uk/id/eprint/811506

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