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Approximate entropy from overnight pulse oximetry for the obstructive sleep apnea syndrome

Hornero, R, Alvarez, D, Abásolo, D, Gómez, C, del Campo, F and Zamarrón, C (2005) Approximate entropy from overnight pulse oximetry for the obstructive sleep apnea syndrome In: 27th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society, 2005-08-31 - 2005-09-03, Shanghai, PEOPLES R CHINA.

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Abstract

The aim of this preliminary study was to asses whether a time series analysis from overnight pulse oximetry by means of Approximate Entropy (ApEn) could yield essential information on the diagnosis of obstructive sleep apnea (OSA) syndrome. We analyzed the oxygen saturation (SaO(2)) signals of 74 patients (44 with a positive diagnosis of OSA and 30 with a negative diagnosis of OSA) by means of ApEn, which quantified the regularity (or complexity) of time series. Results showed that recurrence of apnea events in patients with OSA determined a significant increase in ApEn values with a mean standard deviation (SD) of 1.07 +/- 0.30. A mean +/- SD ApEn value of 0.47 +/- 0.25 was estimated in patients without OSA. We obtained an area under the ROC curve of 0.94. The optimum threshold was selected at 0.81, where we achieved a 79,5% sensitivity and 90% specificity. Further analyses are necessary with new and larger data set to test the potential value of our methodology prospectively.

Item Type: Conference or Workshop Item (UNSPECIFIED)
Authors :
NameEmailORCID
Hornero, RUNSPECIFIEDUNSPECIFIED
Alvarez, DUNSPECIFIEDUNSPECIFIED
Abásolo, DUNSPECIFIEDUNSPECIFIED
Gómez, CUNSPECIFIEDUNSPECIFIED
del Campo, FUNSPECIFIEDUNSPECIFIED
Zamarrón, CUNSPECIFIEDUNSPECIFIED
Date : 2005
Contributors :
ContributionNameEmailORCID
publisherIEEE, UNSPECIFIEDUNSPECIFIED
Uncontrolled Keywords : NOCTURNAL OXIMETRY, HYPOPNEA SYNDROME, HOME OXIMETRY, DIAGNOSIS, COMPLEXITY, MORTALITY, TOOL
Depositing User : Symplectic Elements
Date Deposited : 28 Mar 2017 15:31
Last Modified : 31 Oct 2017 18:28
URI: http://epubs.surrey.ac.uk/id/eprint/811308

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