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Are premorbid abnormal personality traits associated with behavioural and psychological symptoms in dementia?

Prior, J, Abraham, R, Nicholas, H, Chan, T, Vanvlymen, J, Lovestone, S and Boothby, H (2016) Are premorbid abnormal personality traits associated with behavioural and psychological symptoms in dementia? International Journal of Geriatric Psychiatry.

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Abstract

The study aims to investigate associations between behavioural and psychological symptoms of dementia (BPSD) and abnormal premorbid personality traits.Data were obtained from 217 patients with a diagnosis of probable Alzheimer's disease. Behavioural and psychological symptoms of late-onset dementia were assessed with the Neuropsychiatric Inventory. Premorbid personality traits were assessed using the Standardised Assessment of Personality. Abnormal premorbid personality traits were categorised with Diagnostic and Statistical Manual of Mental Disorders fourth edition and International Statistical Classification of Diseases and Related Health Problems-10 diagnostic criteria for personality disorders.Abnormal premorbid personality traits were associated with increased behavioural and psychological symptoms in dementia. Cluster A (solitary/paranoid) premorbid personality traits were associated with anxiety, depression and hallucinations. Cluster C (anxious/dependent) traits were associated with a syndrome of depression.The presence of Clusters A (solitary/paranoid) and C (anxious/dependent) abnormal premorbid personality traits seems to affect the expression of certain behavioural and psychological symptoms in dementia, depression in particular. Copyright © 2016 John Wiley & Sons, Ltd.

Item Type: Article
Subjects : Medical Science
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
AuthorsEmailORCID
Prior, JUNSPECIFIEDUNSPECIFIED
Abraham, RUNSPECIFIEDUNSPECIFIED
Nicholas, HUNSPECIFIEDUNSPECIFIED
Chan, TUNSPECIFIEDUNSPECIFIED
Vanvlymen, JUNSPECIFIEDUNSPECIFIED
Lovestone, SUNSPECIFIEDUNSPECIFIED
Boothby, HUNSPECIFIEDUNSPECIFIED
Date : 10 March 2016
Identification Number : 10.1002/gps.4418
Copyright Disclaimer : Copyright: 2016 John Wiley & Sons, Ltd.
Depositing User : Symplectic Elements
Date Deposited : 15 Jul 2016 15:19
Last Modified : 15 Jul 2016 15:19
URI: http://epubs.surrey.ac.uk/id/eprint/811233

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