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Novel a, a-Bischolesteryl Functional ( Co) Polymers: RAFT Radical Polymerization Synthesis and Preliminary Solution Characterization

Roth, PJ, Davis, TP and Lowe, AB (2014) Novel a, a-Bischolesteryl Functional ( Co) Polymers: RAFT Radical Polymerization Synthesis and Preliminary Solution Characterization MACROMOLECULAR RAPID COMMUNICATIONS, 35 (8). pp. 813-820.

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Abstract

Well-defined poly[pentafluorophenyl (meth)acrylate] (PPFP(M)A) homopolymers are prepared by RAFT radical polymerization mediated by a novel chain transfer agent containing two cholesteryl groups in the R-group fragment. Subsequent reaction with a series of small-molecule amines in the presence of an appropriate Michael acceptor for ω-group end-capping yields a library of novel bischolesteryl functional hydrophilic homopolymers. Two examples of statistical copolymers are also prepared including a biologically relevant sugar derivative. Specific examples of these homopolymers are examined with respect to their ability to self assemble in aqueous media-a process driven entirely by the cholesteryl end groups. In all instances evaluated, and under the preparation conditions examined, the homopolymers aggregate clearly forming polymersomes spanning an impressive size range.

Item Type: Article
Subjects : Chemistry
Authors :
AuthorsEmailORCID
Roth, PJUNSPECIFIEDUNSPECIFIED
Davis, TPUNSPECIFIEDUNSPECIFIED
Lowe, ABUNSPECIFIEDUNSPECIFIED
Date : 1 April 2014
Identification Number : 10.1002/marc.201300889
Uncontrolled Keywords : Science & Technology, Physical Sciences, Polymer Science, POLYMER SCIENCE, cholesterol, end groups, RAFT, self-assembly, vesicles, COPOLYMERS, POLY(N-ISOPROPYLACRYLAMIDE), ESTERS, ENE
Related URLs :
Additional Information : Full text not available from this repository.
Depositing User : Symplectic Elements
Date Deposited : 11 May 2016 11:36
Last Modified : 11 May 2016 11:36
URI: http://epubs.surrey.ac.uk/id/eprint/810669

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