University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Analysis of Urine, Oral fluid and Fingerprints by Liquid Extraction Surface Analysis Coupled to High Resolution MS and MS/MS – Opportunities for Forensic and Biomedical Science

Bailey, MJ, Randall, EC, Costa, C, Salter, T, Race, AM, de Puit, M, Koeberg, M, Baumert, M and Bunch, J (2016) Analysis of Urine, Oral fluid and Fingerprints by Liquid Extraction Surface Analysis Coupled to High Resolution MS and MS/MS – Opportunities for Forensic and Biomedical Science Analytical Methods, 8 (16). pp. 3373-3382.

[img] Text
LESA paper final accepted manuscript.pdf - Accepted version Manuscript
Restricted to Repository staff only until 20 March 2017.
Available under License : See the attached licence file.

Download (636kB)
[img]
Preview
Text (licence)
SRI_deposit_agreement.pdf
Available under License : See the attached licence file.

Download (33kB) | Preview

Abstract

Liquid Extraction Surface Analysis (LESA) is a new, high throughput tool for ambient mass spectrometry. A solvent droplet is deposited from a pipette tip onto a surface and maintains contact with both the surface and the pipette tip for a few seconds before being re-aspirated. The technique is particularly suited to the analysis of trace materials on surfaces due to its high sensitivity and low volume of sample removal. In this work, we assess the suitability of LESA for obtaining detailed chemical profiles of fingerprints, oral fluid and urine, which may be used in future for rapid medical diagnostics or metabolomics studies. We further show how LESA can be used to detect illicit drugs and their metabolites in urine, oral fluid and fingerprints. This makes LESA a potentially useful tool in the growing field of fingerprint chemical analysis, which is relevant not only to forensics but also to medical diagnostics. Finally, we show how LESA can be used to detect the explosive material RDX in contaminated artificial fingermarks.

Item Type: Article
Subjects : Chemistry
Authors :
AuthorsEmailORCID
Bailey, MJUNSPECIFIEDUNSPECIFIED
Randall, ECUNSPECIFIEDUNSPECIFIED
Costa, CUNSPECIFIEDUNSPECIFIED
Salter, TUNSPECIFIEDUNSPECIFIED
Race, AMUNSPECIFIEDUNSPECIFIED
de Puit, MUNSPECIFIEDUNSPECIFIED
Koeberg, MUNSPECIFIEDUNSPECIFIED
Baumert, MUNSPECIFIEDUNSPECIFIED
Bunch, JUNSPECIFIEDUNSPECIFIED
Date : 1 June 2016
Identification Number : 10.1039/C6AY00782A
Copyright Disclaimer : © Royal Society of Chemistry 2016. This is the author's accepted manuscript.
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 08 Apr 2016 10:21
Last Modified : 11 May 2016 10:32
URI: http://epubs.surrey.ac.uk/id/eprint/810381

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800