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Successful corticosteroid-sparing effect of rituximab in the treatment of refractory idiopathic orbital inflammatory disease.

Shao, EH, Karydis, A, Gemenetzi, M and Taylor, SR (2013) Successful corticosteroid-sparing effect of rituximab in the treatment of refractory idiopathic orbital inflammatory disease. Case Rep Ophthalmol, 4 (3). pp. 216-218.

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Abstract

Idiopathic orbital inflammatory disease (IOID) is an idiopathic inflammatory process within the orbit that can result in permanent visual impairment. Although high-dose oral corticosteroids are currently the mainstay of therapy, their long-term usage can cause significant toxicity. We present a case of IOID that was successfully treated with the anti-CD20 monoclonal antibody rituximab following failed steroid sparing with conventional second-line immunosuppressive agents.

Item Type: Article
Subjects : Clinical Medicine
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Clinical and Experimental Medicine
Authors :
AuthorsEmailORCID
Shao, EHUNSPECIFIEDUNSPECIFIED
Karydis, AUNSPECIFIEDUNSPECIFIED
Gemenetzi, MUNSPECIFIEDUNSPECIFIED
Taylor, SRUNSPECIFIEDUNSPECIFIED
Date : 1 November 2013
Identification Number : 10.1159/000356523
Uncontrolled Keywords : Idiopathic orbital inflammatory disease, Rituximab
Related URLs :
Additional Information : This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OAlicense), applicable to the online version of the article only. Distribution permitted for noncommercial purposes only.
Depositing User : Symplectic Elements
Date Deposited : 11 Mar 2016 14:28
Last Modified : 11 Mar 2016 14:28
URI: http://epubs.surrey.ac.uk/id/eprint/810102

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