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Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities.

Henrotin, Y, Chevalier, X, Herrero-Beaumont, G, McAlindon, T, Mobasheri, A, Pavelka, K, Schön, C, Weinans, H, Biesalski, H and Participants at the Hohenheim Consensus Conference in August 29t, (2013) Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities. BMC Res Notes, 6 (1).

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Abstract

The aim of this paper was to provide an overview of the current knowledge and understanding of the potential beneficial physiological effects of glucosamine (GlcN) on joint health. The objective was to reach a consensus on four critical questions and to provide recommendations for future research priorities. To this end, nine scientists from Europe and the United States were selected according to their expertise in this particular field and were invited to participate in the Hohenheim conference held in August 2011. Each expert was asked to address a question that had previously been posed by the chairman of the conference. Based on a systematic review of the literature and the collection of recent data, the experts documented the effects of GlcN on cartilage ageing, metabolic/kinetic and maintenance of joint health as well as reduction of risk of OA development. After extensive debate and discussion the expert panel addressed each question and a general consensus statement was developed, agreeing on the current state-of-the-art and future areas for basic and clinical studies. This paper summarizes the available evidence for beneficial effects of GlcN on joint health and proposes new insight into the design of future clinical trials aimed at identifying beneficial physiological effect of GlcN on joint tissues.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
AuthorsEmailORCID
Henrotin, YUNSPECIFIEDUNSPECIFIED
Chevalier, XUNSPECIFIEDUNSPECIFIED
Herrero-Beaumont, GUNSPECIFIEDUNSPECIFIED
McAlindon, TUNSPECIFIEDUNSPECIFIED
Mobasheri, AUNSPECIFIEDUNSPECIFIED
Pavelka, KUNSPECIFIEDUNSPECIFIED
Schön, CUNSPECIFIEDUNSPECIFIED
Weinans, HUNSPECIFIEDUNSPECIFIED
Biesalski, HUNSPECIFIEDUNSPECIFIED
Participants at the Hohenheim Consensus Conference in August 29t, UNSPECIFIEDUNSPECIFIED
Date : 28 March 2013
Identification Number : 10.1186/1756-0500-6-115
Uncontrolled Keywords : Aging, Cartilage, Chondrocytes, Consensus, Dietary Supplements, Europe, Glucosamine, Glucose, Humans, Joints, Osteoarthritis, Risk Factors, United States
Related URLs :
Additional Information : © 2013 Henrotin et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Depositing User : Symplectic Elements
Date Deposited : 23 Dec 2015 11:36
Last Modified : 23 Dec 2015 11:36
URI: http://epubs.surrey.ac.uk/id/eprint/809564

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