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Intersection of inflammation and herbal medicine in the treatment of osteoarthritis.

Mobasheri, A (2012) Intersection of inflammation and herbal medicine in the treatment of osteoarthritis. Curr Rheumatol Rep, 14 (6). pp. 604-616.

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Abstract

Herbal remedies and dietary supplements have become an important area of research and clinical practice in orthopaedics and rheumatology. Understanding the risks and benefits of using herbal medicines in the treatment of arthritis, rheumatic diseases, and musculoskeletal complaints is a key priority of physicians and their patients. This review discusses the latest advances in the use of herbal medicines for treating osteoarthritis (OA) by focusing on the most significant trends and developments. This paper sets the scene by providing a brief introduction to ethnopharmacology, Ayurvedic medicine, and nutrigenomics before discussing the scientific and mechanistic rationale for targeting inflammatory signalling pathways in OA by use of herbal medicines. Special attention is drawn to the conceptual and practical difficulties associated with translating data from in-vitro experiments to in-vivo studies. Issues relating to the low bioavailability of active ingredients in herbal medicines are discussed, as also is the need for large-scale, randomized clinical trials.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :
AuthorsEmailORCID
Mobasheri, AUNSPECIFIEDUNSPECIFIED
Date : December 2012
Identification Number : 10.1007/s11926-012-0288-9
Uncontrolled Keywords : Humans, Inflammation, Osteoarthritis, Phytotherapy, Plant Preparations
Related URLs :
Additional Information : Copyright The Author(s) 2012. This article is published with open access at Springerlink.com
Depositing User : Symplectic Elements
Date Deposited : 23 Dec 2015 11:50
Last Modified : 23 Dec 2015 11:50
URI: http://epubs.surrey.ac.uk/id/eprint/809552

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