University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Both resistance- and endurance-type exercise reduce the prevalence of hyperglycaemia in individuals with impaired glucose tolerance and in insulin-treated and non-insulin-treated type 2 diabetic patients

van Dijk, J-W, Manders, RJF, Tummers, K, Bonomi, AG, Stehouwer, CDA, Hartgens, F and van Loon, LJC (2012) Both resistance- and endurance-type exercise reduce the prevalence of hyperglycaemia in individuals with impaired glucose tolerance and in insulin-treated and non-insulin-treated type 2 diabetic patients DIABETOLOGIA, 55 (5). pp. 1273-1282.

[img]
Preview
Text
v. Dijk Diab 2012.pdf - ["content_typename_Accepted version (post-print)" not defined]
Available under License : See the attached licence file.

Download (276kB) | Preview
[img]
Preview
PDF (licence)
SRI_deposit_agreement.pdf
Available under License : See the attached licence file.

Download (33kB) | Preview

Abstract

Aims/hypothesis The present study compares the impact of endurance- vs resistance-type exercise on subsequent 24 h blood glucose homeostasis in individuals with impaired glucose tolerance (IGT) and type 2 diabetes. Methods Fifteen individuals with IGT, 15 type 2 diabetic patients treated with exogenous insulin (INS), and 15 type 2 diabetic patients treated with oral glucose-lowering medication (OGLM) participated in a randomised crossover experiment. Participants were studied on three occasions for 3 days under strict dietary standardisation, but otherwise free-living conditions. Blood glucose homeostasis was assessed by ambulatory continuous glucose monitoring over the 24 h period following a 45 min session of resistance-type exercise (75% one repetition maximum), endurance-type exercise (50% maximum workload capacity) or no exercise at all. Results Average 24 h blood glucose concentrations were reduced from 7.4±0.2, 9.6±0.5 and 9.2±0.7 mmol/l during the control experiment to 6.9±0.2, 8.6±0.4 and 8.1±0.5 mmol/l (resistance-type exercise) and 6.8±0.2, 8.6±0.5 and 8.5±0.5 mmol/l (endurance-type exercise) over the 24 h period following a single bout of exercise in the IGT, OGLM and INS groups, respectively (p< 0.001 for both treatments). The prevalence of hyperglycaemia (blood glucose > 10 mmol/l) was reduced by 35±7 and 33±11% over the 24 h period following a single session of resistanceand endurance-type exercise, respectively (p< 0.001 for both treatments). Conclusions/interpretation A single session of resistanceor endurance-type exercise substantially reduces the prevalence of hyperglycaemia during the subsequent 24 h period in individuals with IGT, and in insulin-treated and non-insulin-treated type 2 diabetic patients. Both resistance- and endurance-type exercise can be integrated in exercise intervention programmes designed to improve glycaemic control. Trial registration: Clinicaltrials.gov NCT00945165 Funding: The Netherlands Organization for Health Research and Development (ZonMw, the Netherlands). © 2011 The Author(s).

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Nutritional Sciences
Authors :
AuthorsEmailORCID
van Dijk, J-WUNSPECIFIEDUNSPECIFIED
Manders, RJFUNSPECIFIEDUNSPECIFIED
Tummers, KUNSPECIFIEDUNSPECIFIED
Bonomi, AGUNSPECIFIEDUNSPECIFIED
Stehouwer, CDAUNSPECIFIEDUNSPECIFIED
Hartgens, FUNSPECIFIEDUNSPECIFIED
van Loon, LJCUNSPECIFIEDUNSPECIFIED
Date : 1 May 2012
Identification Number : 10.1007/s00125-011-2380-5
Uncontrolled Keywords : Science & Technology, Life Sciences & Biomedicine, Endocrinology & Metabolism, ENDOCRINOLOGY & METABOLISM, Continuous glucose monitoring, Exercise, Glycaemic control, Postprandial hyperglycaemia, Type 2 diabetes mellitus, SKELETAL-MUSCLE, POSTPRANDIAL HYPERGLYCEMIA, AUTONOMIC FAILURE, GLYCEMIC CONTROL, CONTROLLED-TRIAL, OLDER-ADULTS, SENSITIVITY, TRANSPORT, MEN, PHOSPHORYLATION
Related URLs :
Additional Information : Copyright The Author(s) 2011. This article is published with open access at Springerlink.com
Depositing User : Symplectic Elements
Date Deposited : 23 Dec 2015 14:42
Last Modified : 23 Dec 2015 14:42
URI: http://epubs.surrey.ac.uk/id/eprint/809354

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800