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Manipulation of herpes simplex virus type 1 by dielectrophoresis

Hughes, MP, Morgan, H, Rixon, FJ, Burt, JPH and Pethig, R (1998) Manipulation of herpes simplex virus type 1 by dielectrophoresis BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1425 (1). pp. 119-126.

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Abstract

The frequency-dependent dielectrophoretic behaviour of an enveloped mammalian virus, herpes simplex virus type 1 is described. It is demonstrated that over the range 10 kHz-20 MHz, these viral particles, when suspended in an aqueous medium of conductivity 5 mS m(-1), can be manipulated by both positive and negative dielectrophoresis using microfabricated electrode arrays. The observed transition from positive to negative dielectrophoresis at frequencies around 4.5 MHz is in qualitative agreement with a simple model of the virus as a conducting particle surrounded by an insulating membrane.

Item Type: Article
Authors :
AuthorsEmailORCID
Hughes, MPUNSPECIFIEDUNSPECIFIED
Morgan, HUNSPECIFIEDUNSPECIFIED
Rixon, FJUNSPECIFIEDUNSPECIFIED
Burt, JPHUNSPECIFIEDUNSPECIFIED
Pethig, RUNSPECIFIEDUNSPECIFIED
Date : 16 September 1998
Identification Number : 10.1016/S0304-4165(98)00058-0
Uncontrolled Keywords : Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Biophysics, BIOCHEMISTRY & MOLECULAR BIOLOGY, BIOPHYSICS, AC electrokinetics, dielectric property, nanotechnology, particle manipulation, FREQUENCY ELECTRIC-FIELDS, CELLS, DIFFERENTIATION, ELECTROROTATION, PARTICLES
Related URLs :
Additional Information : © 1998. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Depositing User : Symplectic Elements
Date Deposited : 30 Sep 2015 13:51
Last Modified : 30 Sep 2015 13:51
URI: http://epubs.surrey.ac.uk/id/eprint/808542

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