Optimizing particle collection for enhanced surface-based biosensors

Hoettges, KF, Hughes, MP, Cotton, A, Hopkins, NAE and McDonnell, MB (2003) Optimizing particle collection for enhanced surface-based biosensors IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE, 22 (6). pp. 68-74.

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Abstract

In this article, electrode structures that combine dielectrophoretic effects with electrohydrodynamic fluid flow to concentrate particles on active sensor surfaces were presented. To optimize the collection effect on a surface, a novel electrode configuration called zipper electrodes has been developed. The local enrichment effect of these electrodes is such that particles at local concentration of 5×103 spores/mL can be collected using a single electrode pad. The fluid flow induced in the bulk flow is an efficient mechanism especially for very small particles, since the dielectrophoretic forces working on these particles are normally very small and do not penetrate the liquid as far as the vortex induced by combined dielectrophoresis/fluid flow does. The bulk flow makes it also a very versatile method that can extract a wide range of particles out of the liquid.

Item Type:	Article
Divisions :	Faculty of Engineering and Physical Sciences > Mechanical Engineering Sciences
Authors :	Hoettges, KF, Hughes, MP, Cotton, A, Hopkins, NAE and McDonnell, MB
Date :	1 November 2003
DOI :	10.1109/MEMB.2003.1266049
Uncontrolled Keywords :	Science & Technology, Technology, Life Sciences & Biomedicine, Engineering, Biomedical, Medical Informatics, Engineering, ENGINEERING, BIOMEDICAL, MEDICAL INFORMATICS, DIELECTROPHORETIC BEHAVIOR, COLLOIDAL PARTICLES, OPTICAL TECHNIQUE, LIGHT-SCATTERING, FLUID-FLOW, SEPARATION, MICROELECTRODES, MICROORGANISMS, BIOPARTICLES, CELLS
Related URLs :	Author
Additional Information :	© 2003 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Depositing User :	Symplectic Elements
Date Deposited :	13 Oct 2015 09:03
Last Modified :	06 Jul 2019 05:14
URI:	http://epubs.surrey.ac.uk/id/eprint/808519

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