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An experimental evaluation of the Agility MLC for motion-compensated VMAT delivery.

Davies, GA, Clowes, P, Bedford, JL, Evans, PM, Webb, S and Poludniowski, G (2013) An experimental evaluation of the Agility MLC for motion-compensated VMAT delivery. Phys Med Biol, 58 (13). pp. 4643-4657.

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Abstract

An algorithm for dynamic multileaf-collimator (dMLC) tracking of a target performing a known a priori, rigid-body motion during volumetric modulated arc therapy (VMAT), has been experimentally validated and applied to investigate the potential of the Agility (Elekta AB, Stockholm, Sweden) multileaf-collimator (MLC) for use in motion-compensated VMAT delivery. For five VMAT patients, dosimetric measurements were performed using the Delta(4) radiation detector (ScandiDos, Uppsala, Sweden) and the accuracy of dMLC tracking was evaluated using a gamma-analysis, with threshold levels of 3% for dose and 3 mm for distance-to-agreement. For a motion trajectory with components in two orthogonal directions, the mean gamma-analysis pass rate without tracking was found to be 58.0%, 59.0% and 60.9% and was increased to 89.1%, 88.3% and 93.1% with MLC tracking, for time periods of motion of 4 s, 6 s and 10 s respectively. Simulations were performed to compare the efficiency of the Agility MLC with the MLCi MLC when used for motion-compensated VMAT delivery for the same treatment plans and motion trajectories. Delivery time increases from a static-tumour to dMLC-tracking VMAT delivery were observed in the range 0%–20% for the Agility, and 0%–57% with the MLCi, indicating that the increased leaf speed of the Agility MLC is beneficial for MLC tracking during lung radiotherapy.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Electronic Engineering > Centre for Vision Speech and Signal Processing
Authors :
AuthorsEmailORCID
Davies, GAUNSPECIFIEDUNSPECIFIED
Clowes, PUNSPECIFIEDUNSPECIFIED
Bedford, JLUNSPECIFIEDUNSPECIFIED
Evans, PMUNSPECIFIEDUNSPECIFIED
Webb, SUNSPECIFIEDUNSPECIFIED
Poludniowski, GUNSPECIFIEDUNSPECIFIED
Date : 7 July 2013
Identification Number : 10.1088/0031-9155/58/13/4643
Related URLs :
Additional Information : Copyright 2013 Institute of Physics. This is the author's accepted manuscript.
Depositing User : Symplectic Elements
Date Deposited : 17 Dec 2014 14:40
Last Modified : 20 Dec 2014 14:36
URI: http://epubs.surrey.ac.uk/id/eprint/806914

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