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Proton computed tomography reconstruction using a backprojection-then-filtering approach.

Poludniowski, G, Allinson, NM and Evans, PM (2014) Proton computed tomography reconstruction using a backprojection-then-filtering approach. Phys Med Biol, 59 (24). pp. 7905-7918.

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Abstract

A novel approach to proton CT reconstruction using backprojection-then-filtering (BPF) is proposed. A list-mode algorithm is formulated accommodating non-linear proton paths. The analytical form is derived for the deblurring kernel necessary for the filtering step. Further, a finite matrix correction is derived to correct for the limited size of the backprojection matrix. High quantitative accuracy in relative stopping power is demonstrated (⩽0.1%) using Monte Carlo simulations. This accuracy makes the algorithm a promising candidate for future proton CT systems in proton therapy applications. For the purposes of reconstruction, each proton path in the object-of-interest was estimated based on a cubic spline fit to the proton entry and exit vectors. The superior spatial-resolution of the BPF method over the standard filtering-then-backprojection approach is demonstrated. As the BPF algorithm requires only one backprojection and filtering operation on a scan data set, it also offers computational advantages over an iterative reconstruction approach.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Electronic Engineering > Centre for Vision Speech and Signal Processing
Authors :
AuthorsEmailORCID
Poludniowski, GUNSPECIFIEDUNSPECIFIED
Allinson, NMUNSPECIFIEDUNSPECIFIED
Evans, PMUNSPECIFIEDUNSPECIFIED
Date : December 2014
Identification Number : 10.1088/0031-9155/59/24/7905
Related URLs :
Additional Information : Copyright 2014 Institute of Physics. This is the author's accepted manuscript.
Depositing User : Symplectic Elements
Date Deposited : 10 Dec 2014 17:15
Last Modified : 26 Nov 2015 02:08
URI: http://epubs.surrey.ac.uk/id/eprint/806898

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