In vitro induction of functional allergen-specific CD4+ CD25high Treg cells in horses affected with insect bite hypersensitivity.

Hamza, E, Akdis, CA, Wagner, B, Steinbach, F and Marti, E (2013) In vitro induction of functional allergen-specific CD4+ CD25high Treg cells in horses affected with insect bite hypersensitivity. Clin Exp Allergy, 43 (8). pp. 889-901.

	Text 61 Hamza, CEI 2013.pdf - ["content_typename_UNSPECIFIED" not defined] Restricted to Repository staff only Available under License : See the attached licence file. Download (420kB)
	PDF (licence) SRI_deposit_agreement.pdf Restricted to Repository staff only Available under License : See the attached licence file. Download (33kB)

Abstract

Insect bite hypersensitivity (IBH) is a recurrent allergic dermatitis of horses with similarities to human atopic eczema, caused by bites of insects of the genus Culicoides. Previous studies suggested a dysregulated T cell tolerance to Culicoides allergen in IBH-affected horses.

Item Type:	Article
Authors :	Authors Email ORCID Hamza, E UNSPECIFIED UNSPECIFIED Akdis, CA UNSPECIFIED UNSPECIFIED Wagner, B UNSPECIFIED UNSPECIFIED Steinbach, F UNSPECIFIED UNSPECIFIED Marti, E UNSPECIFIED UNSPECIFIED
Date :	August 2013
Identification Number :	https://doi.org/10.1111/cea.12131
Uncontrolled Keywords :	CD4+ CD25+ T cells, FoxP3, IBH, IL-10, IL-4, Icelandic horses, Treg expansion, Treg induction, Treg suppression, allergy, rIL-2 and rTGF-β1., retinoic acid and rapamycin, Allergens, Animals, Antigens, CD4, Cytokines, Epitopes, T-Lymphocyte, Female, Forkhead Transcription Factors, Horses, Hypersensitivity, Immune Tolerance, Insect Bites and Stings, Interleukin-2, Interleukin-2 Receptor alpha Subunit, Lymphocyte Activation, Male, T-Lymphocytes, Regulatory, Transforming Growth Factor beta
Related URLs :	Author
Depositing User :	Symplectic Elements
Date Deposited :	28 Mar 2017 10:51
Last Modified :	28 Mar 2017 10:51
URI:	http://epubs.surrey.ac.uk/id/eprint/806884

Actions (login required)

View Item

Downloads