In vitro induction of functional allergen-specific CD4+ CD25high Treg cells in horses affected with insect bite hypersensitivity.
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Hamza, E, Akdis, CA, Wagner, B, Steinbach, F and Marti, E (2013) In vitro induction of functional allergen-specific CD4+ CD25high Treg cells in horses affected with insect bite hypersensitivity. Clin Exp Allergy, 43 (8). pp. 889-901.
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Abstract
Insect bite hypersensitivity (IBH) is a recurrent allergic dermatitis of horses with similarities to human atopic eczema, caused by bites of insects of the genus Culicoides. Previous studies suggested a dysregulated T cell tolerance to Culicoides allergen in IBH-affected horses.
Item Type: | Article |
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Divisions : | Surrey research (other units) |
Authors : | Hamza, E, Akdis, CA, Wagner, B, Steinbach, F and Marti, E |
Date : | August 2013 |
DOI : | 10.1111/cea.12131 |
Uncontrolled Keywords : | CD4+ CD25+ T cells, FoxP3, IBH, IL-10, IL-4, Icelandic horses, Treg expansion, Treg induction, Treg suppression, allergy, rIL-2 and rTGF-β1., retinoic acid and rapamycin, Allergens, Animals, Antigens, CD4, Cytokines, Epitopes, T-Lymphocyte, Female, Forkhead Transcription Factors, Horses, Hypersensitivity, Immune Tolerance, Insect Bites and Stings, Interleukin-2, Interleukin-2 Receptor alpha Subunit, Lymphocyte Activation, Male, T-Lymphocytes, Regulatory, Transforming Growth Factor beta |
Related URLs : | |
Depositing User : | Symplectic Elements |
Date Deposited : | 28 Mar 2017 10:51 |
Last Modified : | 24 Jan 2020 12:32 |
URI: | http://epubs.surrey.ac.uk/id/eprint/806884 |
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