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Neurobehavioural changes in patients following brain tumour: patients and relatives perspective

Gregg, N, Arber, A, Ashkan, K, Brazil, L, Bhangoo, R, Beaney, R, Gullan, R, Hurwitz, V, Costello, A and Yágüez, L (2014) Neurobehavioural changes in patients following brain tumour: patients and relatives perspective Supportive Care in Cancer.

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Abstract

Background: Patients and relatives experiences of behavioural and personality changes following brain tumour were assessed to determine whether these changes are more prominent in the experience of patients with frontal tumours and their relatives as a first step to evaluate the need to develop appropriate support and management of such changes, which have a substantial impact on social functioning, and ultimately to improve quality of life. Methods: Patients and relatives rated the patients’ current levels of apathy, disinhibition and executive dysfunction on the Frontal Systems Behaviour Scale. Patients also completed the Hospital Anxiety and Depression Scale. The data from 28 patients with frontal tumours and 24 of their relatives, and 27 patients with non-frontal tumours and 25 of their relatives, were analysed. Results: Patients with frontal tumours rated themselves significantly higher than patients with non-frontal tumours on all frontal systems-related behaviours. The number of patients reporting clinical levels of difficulty was significantly greater in patients with frontal tumours for disinhibition. The ratings of relatives of patients with frontal tumours were significantly higher than those of relatives of patients with non-frontal tumours for apathy. Clinically significant levels of apathy and executive dysfunction were however reported by at least 40% of patients and relatives regardless of tumour location. Clinical levels of anxiety were reported by significantly more patients with frontal tumours than those with non-frontal tumours. Conclusion: Support and management of behavioural and personality change for patients with brain tumours and their relatives, regardless of tumour location, would be most appropriate.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Health Sciences
Authors :
AuthorsEmailORCID
Gregg, NUNSPECIFIEDUNSPECIFIED
Arber, AUNSPECIFIEDUNSPECIFIED
Ashkan, KUNSPECIFIEDUNSPECIFIED
Brazil, LUNSPECIFIEDUNSPECIFIED
Bhangoo, RUNSPECIFIEDUNSPECIFIED
Beaney, RUNSPECIFIEDUNSPECIFIED
Gullan, RUNSPECIFIEDUNSPECIFIED
Hurwitz, VUNSPECIFIEDUNSPECIFIED
Costello, AUNSPECIFIEDUNSPECIFIED
Yágüez, LUNSPECIFIEDUNSPECIFIED
Date : 2 June 2014
Identification Number : 10.1007/s00520-014-2291-3
Uncontrolled Keywords : brain tumour, frontal lobe, personality change, apathy, anxiety and depression
Additional Information : The original publication is available at http://www.springerlink.com
Depositing User : Symplectic Elements
Date Deposited : 24 Jun 2014 14:25
Last Modified : 28 May 2015 01:08
URI: http://epubs.surrey.ac.uk/id/eprint/805618

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