University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Engineered Nanomaterials: Knowledge Gaps in Fate, Exposure, Toxicity, and Future Directions

Kumar, A, , Kumar, P, , Anandan, A, Fernandes, TF, Ayoko, GA and Biskos, J, (2014) Engineered Nanomaterials: Knowledge Gaps in Fate, Exposure, Toxicity, and Future Directions Journal of Nanomaterials, 2014, 130198.

[img]
Preview
Text
Kumar et al. (2014)_JNM ENP Review.pdf - ["content_typename_UNSPECIFIED" not defined]
Available under License : See the attached licence file.

Download (1MB) | Preview
[img]
Preview
PDF (licence)
SRI_deposit_agreement.pdf
Available under License : See the attached licence file.

Download (33kB) | Preview

Abstract

The aim of this study is to identify current knowledge gaps in fate, exposure, and toxicity of engineered nanomaterials (ENMs), highlight research gaps, and suggest future research directions. Humans and other living organisms are exposed to ENMs during production or use of products containing them. To assess the hazards of ENMs, it is important to assess their physiochemical properties and try to relate them to any observed hazard. However, the full determination of these relationships is currently limited by the lack of empirical data. Moreover, most toxicity studies do not use realistic environmental exposure conditions for determining dose-response parameters, affecting the accurate estimation of health risks associated with the exposure to ENMs. Regulatory aspects of nanotechnology are still developing and are currently the subject of much debate. Synthesis of available studies suggests a number of open questions. These include (i) developing a combination of different analytical methods for determining ENM concentration, size, shape, surface properties, and morphology in different environmental media, (ii) conducting toxicity studies using environmentally relevant exposure conditions and obtaining data relevant to developing quantitative nanostructure-toxicity relationships (QNTR), and (iii) developing guidelines for regulating exposure of ENMs in the environment.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Civil and Environmental Engineering
Authors :
AuthorsEmailORCID
Kumar, A, UNSPECIFIEDUNSPECIFIED
Kumar, P, UNSPECIFIEDUNSPECIFIED
Anandan, AUNSPECIFIEDUNSPECIFIED
Fernandes, TFUNSPECIFIEDUNSPECIFIED
Ayoko, GAUNSPECIFIEDUNSPECIFIED
Biskos, J, UNSPECIFIEDUNSPECIFIED
Date : 12 May 2014
Identification Number : 10.1155/2014/130198
Related URLs :
Additional Information : Copyright © 2014 Arun Kumar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Depositing User : Symplectic Elements
Date Deposited : 11 Jul 2014 10:01
Last Modified : 17 Aug 2014 01:34
URI: http://epubs.surrey.ac.uk/id/eprint/805544

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800