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Evaluation of a novel wafer-scale CMOS APS X-ray detector for use in mammography

Konstantinidis, AC, Zheng, Y, Olivo, A, Speller, RD, Bliznakova, K, Yip, M, Wells, K, Anaxagoras, T and Allinson, N (2012) Evaluation of a novel wafer-scale CMOS APS X-ray detector for use in mammography IEEE Nuclear Science Symposium Conference Record. pp. 3254-3260.

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Abstract

The most important factors that affect the image quality are contrast, spatial resolution and noise. These factors and their relationship are quantitatively described by the Contrast-to-Noise Ratio (CNR), Signal-to-Noise Ratio (SNR), Modulation Transfer Function (MTF), Noise Power Spectrum (NPS) and Detective Quantum Efficiency (DQE) parameters. The combination of SNR, MTF and NPS determines the DQE, which represents the ability to visualize object details of a certain size and contrast at a given dose. In this study the performance of a novel large area Complementary Metal-Oxide-Semiconductor (CMOS) Active Pixel Sensor (APS) X-ray detector, called DynAMITe (Dynamic range Adjustable for Medical Imaging Technology), was investigated and compared to other three digital mammography systems (namely a) Large Area Sensor (LAS), b) Hamamatsu C9732DK, and c) Anrad SMAM), in terms of physical characteristics and evaluation of the image quality. DynAMITe detector consists of two geometrically superimposed grids: a) 2560 × 2624 pixels at 50 μm pitch, named Sub-Pixels (SP camera) and b) 1280 × 1312 pixels at 100 μm pitch, named Pixels (P camera). The X-ray performance evaluation of DynAMITe SP detector demonstrated high DQE results (0.58 to 0.64 at 0.5 lp/mm). Image simulation based on the X-ray performance of the detectors was used to predict and compare the mammographic image quality using ideal software phantoms: a) one representing two three dimensional (3-D) breasts of various thickness and glandularity to estimate the CNR between simulated microcalcifications and the background, and b) the CDMAM 3.4 test tool for a contrast-detail analysis of small thickness and low contrast objects. The results show that DynAMITe SP detector results in high CNR and contrast-detail performance. © 2012 IEEE.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Electronic Engineering
Authors :
AuthorsEmailORCID
Konstantinidis, ACUNSPECIFIEDUNSPECIFIED
Zheng, YUNSPECIFIEDUNSPECIFIED
Olivo, AUNSPECIFIEDUNSPECIFIED
Speller, RDUNSPECIFIEDUNSPECIFIED
Bliznakova, KUNSPECIFIEDUNSPECIFIED
Yip, MUNSPECIFIEDUNSPECIFIED
Wells, KUNSPECIFIEDUNSPECIFIED
Anaxagoras, TUNSPECIFIEDUNSPECIFIED
Allinson, NUNSPECIFIEDUNSPECIFIED
Date : 2012
Identification Number : 10.1109/NSSMIC.2012.6551742
Additional Information : © 2012 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Depositing User : Symplectic Elements
Date Deposited : 01 Apr 2014 10:28
Last Modified : 26 Sep 2014 13:33
URI: http://epubs.surrey.ac.uk/id/eprint/805190

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