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Impedimetric microanalysis system for deep vein thrombosis point-of-care testing

Renault, NJ, Korri-Youssoufi, H, Kyselovik, J, Auger, V, Errachid, A, Mills, CA, Strohhöfer, C and Ali, Z (2008) Impedimetric microanalysis system for deep vein thrombosis point-of-care testing In: EMBC '08, 2008-08-20 - 2008-08-24, Vancouver, Canada.

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Abstract

Deep Vein Thrombosis (DVT) and the associated condition of Pulmonary Embolism (PE) are the most common cause of unexpected death in developed nations. DVT is an internal clot formed in one of the body's deep veins, typically in the leg. If a part of the clot breaks free and moves into the lung, it can lead to pulmonary embolism (PE) which is often fatal. D-dimer is a recognised marker for the diagnosis of thrombus and is routinely used by skilled technical staff as part of an ELISA technique in hospital laboratories. Current D-dimer point-of-care tests are not sufficiently quantitative to allow them to be used to exclude DVT/PE. As a consequence, clinicians need to rely on the use of expensive Doppler ultrasound imaging (DUS), creating additional pressure on national health services. The DUS examination can take several days, during which time heparin is required to be administered to the patient. There is increasing in the development of low cost Lab-on-a-chip systems that will allow chemical and biological processing by non-specialist staff. A low cost, easy to use, portable and quantitative device for DVT/PE would be highly desirable since it would provide reliable diagnosis and aid faster treatment and recovery as well as lower healthcare provider costs.

Item Type: Conference or Workshop Item (Conference Paper)
Divisions : Faculty of Engineering and Physical Sciences > Electronic Engineering > Advanced Technology Institute > Nano-Electronics Centre
Authors :
AuthorsEmailORCID
Renault, NJUNSPECIFIEDUNSPECIFIED
Korri-Youssoufi, HUNSPECIFIEDUNSPECIFIED
Kyselovik, JUNSPECIFIEDUNSPECIFIED
Auger, VUNSPECIFIEDUNSPECIFIED
Errachid, AUNSPECIFIEDUNSPECIFIED
Mills, CAUNSPECIFIEDUNSPECIFIED
Strohhöfer, CUNSPECIFIEDUNSPECIFIED
Ali, ZUNSPECIFIEDUNSPECIFIED
Date : 2008
Identification Number : 10.1109/IEMBS.2008.4649544
Additional Information : © 2008 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Depositing User : Symplectic Elements
Date Deposited : 06 Nov 2013 10:06
Last Modified : 09 Jun 2014 13:33
URI: http://epubs.surrey.ac.uk/id/eprint/804161

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