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The chemistry and biological activity of the Hyacinthaceae.

Mulholland, DA, Schwikkard, SL and Crouch, NR (2013) The chemistry and biological activity of the Hyacinthaceae. Nat Prod Rep, 30 (9). pp. 1165-1210.

Hyacinthaceae Review 2013.pdf
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Covering: 1914 to 2012The Hyacinthaceae (sensu APGII), with approximately 900 species in about 70 genera, can be divided into three main subfamilies, the Hyacinthoideae, the Urgineoideae and the Ornithogaloideae, with a small fourth subfamily the Oziroëoideae, restricted to South America. The plants included in this family have long been used in traditional medicine for a wide range of medicinal applications. This, together with some significant toxicity to livestock has led to the chemical composition of many of the species being investigated. The compounds found are, for the most part, subfamily-restricted, with homoisoflavanones and spirocyclic nortriterpenoids characterising the Hyacinthoideae, bufadienolides characterising the Urgineoideae, and cardenolides and steroidal glycosides characterising the Ornithogaloideae. The phytochemical profiles of 38 genera of the Hyacinthaceae will be discussed as well as any biological activity associated with both crude extracts and compounds isolated. The Hyacinthaceae of southern Africa were last reviewed in 2000 (T. S. Pohl, N. R. Crouch and D. A. Mulholland, Curr. Org. Chem., 2000, 4, 1287-1324; ); the current contribution considers the family at a global level.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Chemistry
Authors :
Mulholland, DA
Schwikkard, SL
Crouch, NR
Date : 29 July 2013
DOI : 10.1039/c3np70008a
Related URLs :
Additional Information : This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Depositing User : Symplectic Elements
Date Deposited : 29 May 2014 15:48
Last Modified : 16 Aug 2014 01:33

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