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A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood

McMurray, AA, Renault, NJ, Kyselovik, J, Mills, CA, Santha, H, Strohhöfer, C and Ali, Z (2007) A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. pp. 115-118.

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Abstract

There is an unmet medical need for a more reliable and earlier assessment of patients suspected of having a deep vein thrombosis. We describe a novel approach which is developing a highly reliable, accurate, portable and handheld prototype medical diagnostic device to improve radically the speed, accuracy and reliability with which DVT and related blood clotting conditions can be assessed. The device will measure whole blood concentration of D-dimer, a recognized biomarker of increased blood clotting activity, and through innovation in the development of a novel detection, measurement and reporting system, will offer the opportunity to use the test in the point of care setting. The device combines innovation in antibody bio-engineering for high specificity immunoassay-based diagnostics and nano/micro engineered impedimetric analysis electrodes incorporating a biocompatible polymer substrate with development of a disposable microfluidic manifold specifically enabling diagnostics at the point-of-first-contact. © 2007 IEEE.

Item Type: Article
Authors :
NameEmailORCID
McMurray, AAUNSPECIFIEDUNSPECIFIED
Renault, NJUNSPECIFIEDUNSPECIFIED
Kyselovik, JUNSPECIFIEDUNSPECIFIED
Mills, CAUNSPECIFIEDUNSPECIFIED
Santha, HUNSPECIFIEDUNSPECIFIED
Strohhöfer, CUNSPECIFIEDUNSPECIFIED
Ali, ZUNSPECIFIEDUNSPECIFIED
Date : 2007
Identification Number : 10.1109/IEMBS.2007.4352236
Depositing User : Symplectic Elements
Date Deposited : 28 Mar 2017 13:47
Last Modified : 31 Oct 2017 15:04
URI: http://epubs.surrey.ac.uk/id/eprint/770385

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