University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Transparent micro- and nanopatterned poly(lactic acid) for biomedical applications.

Mills, CA, Navarro, M, Engel, E, Martinez, E, Ginebra, MP, Planell, J, Errachid, A and Samitier, J (2006) Transparent micro- and nanopatterned poly(lactic acid) for biomedical applications. Journal of Biomedical Materials Research Part A, 76 (4). pp. 781-787.

[img] Text
PLA paper final.pdf
Restricted to Repository staff only
Available under License : See the attached licence file.

Download (855kB)
[img] Text (licence)
Restricted to Repository staff only

Download (33kB)


The formation of structures in poly(lactic acid) has been investigated with respect to producing areas of regular, superficial features with dimensions comparable to those of cells or biological macromolecules. Nanoembossing, a novel method of pattern replication in polymers, has been used for the production of features ranging from tens of micrometers, covering areas up to 1 cm(2), down to hundreds of nanometers. Both micro- and nanostructures are faithfully replicated. Contact-angle measurements suggest that positive microstructuring of the polymer (where features protrude from the polymer surface) produces a more hydrophilic surface than negative microstructuring. The ability to structure the surface of the poly(lactic acid), allied to the polymer's postprocessing transparency and proven biocompatibility, means that thin films produced in this way will be useful for bioengineers studying the interaction of micro- and nanodimensioned features with biological specimen, with regard to tissue engineering, for example.

Item Type: Article
Authors :
Mills, CA
Navarro, M
Engel, E
Martinez, E
Ginebra, MP
Planell, J
Errachid, A
Samitier, J
Date : 15 March 2006
DOI : 10.1002/jbm.a.30539
Uncontrolled Keywords : Biocompatible Materials, Cell Line, Lactic Acid, Nanotechnology, Polymers
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 28 Mar 2017 13:43
Last Modified : 31 Oct 2017 14:59

Actions (login required)

View Item View Item


Downloads per month over past year

Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800