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The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence.

Butler, RE, Brodin, P, Jang, J, Jang, MS, Robertson, BD, Gicquel, B and Stewart, GR (2012) The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence. PLoS One, 7 (10).

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Abstract

An important mechanism of Mycobacterium tuberculosis pathogenesis is the ability to control cell death pathways in infected macrophages: apoptotic cell death is bactericidal, whereas necrotic cell death may facilitate bacterial dissemination and transmission.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Microbial and Cellular Sciences
Authors :
AuthorsEmailORCID
Butler, REUNSPECIFIEDUNSPECIFIED
Brodin, PUNSPECIFIEDUNSPECIFIED
Jang, JUNSPECIFIEDUNSPECIFIED
Jang, MSUNSPECIFIEDUNSPECIFIED
Robertson, BDUNSPECIFIEDUNSPECIFIED
Gicquel, BUNSPECIFIEDUNSPECIFIED
Stewart, GRUNSPECIFIEDUNSPECIFIED
Date : 2012
Identification Number : 10.1371/journal.pone.0047573
Depositing User : Symplectic Elements
Date Deposited : 04 Feb 2013 11:37
Last Modified : 23 Sep 2013 19:59
URI: http://epubs.surrey.ac.uk/id/eprint/745929

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