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Micro- and nanostructuring of freestanding, biodegradable, thin sheets of chitosan via soft lithography.

Fernandez, JG, Mills, CA, Martinez, E, Lopez-Bosque, MJ, Sisquella, X, Errachid, A and Samitier, J (2008) Micro- and nanostructuring of freestanding, biodegradable, thin sheets of chitosan via soft lithography. Journal of Biomedical Materials Research, 85 (1). pp. 242-247.

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Abstract

A technique for imparting micro- and nanostructured topography into the surface of freestanding thin sheets of chitosan is described. Both micro- and nanometric surface structures have been produced using soft lithography. The soft lithography method, based on solvent evaporation, has allowed structures approximately 60 nm tall and approximately 500 x 500 nm(2) to be produced on freestanding approximately 0.5 mm thick sheets of the polymer when cured at 293 K, and structures approximately 400 nm tall and 5 x 5 microm(2) to be produced when cured at 283 K. Nonstructured chitosan thin sheets (approximately 200 microm thick) show excellent optical transmission properties in the visible portion of the electromagnetic spectrum. The structured sheets can be used for applications where optical microscopic analysis is required, such as cell interaction experiments and tissue engineering.

Item Type: Article
Authors :
AuthorsEmailORCID
Fernandez, JGUNSPECIFIEDUNSPECIFIED
Mills, CAUNSPECIFIEDUNSPECIFIED
Martinez, EUNSPECIFIEDUNSPECIFIED
Lopez-Bosque, MJUNSPECIFIEDUNSPECIFIED
Sisquella, XUNSPECIFIEDUNSPECIFIED
Errachid, AUNSPECIFIEDUNSPECIFIED
Samitier, JUNSPECIFIEDUNSPECIFIED
Date : April 2008
Identification Number : https://doi.org/10.1002/jbm.a.31561
Uncontrolled Keywords : Biocompatible Materials, Chitosan, Nanotechnology, Prostheses and Implants, Spectrophotometry, Tissue Engineering
Depositing User : Symplectic Elements
Date Deposited : 28 Mar 2017 14:12
Last Modified : 28 Mar 2017 14:12
URI: http://epubs.surrey.ac.uk/id/eprint/736489

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