Clinical update: melatonin and sleep disorders

Arendt, J, Van Someren, EJW, Appleton, R, Skene, DJ and Akerstedt, T (2008) Clinical update: melatonin and sleep disorders CLINICAL MEDICINE, 8 (4). pp. 381-383.

	Text s7.pdf Restricted to Repository staff only Available under License : See the attached licence file. Download (153kB)
	Text (licence) SRI_deposit_agreement.pdf Restricted to Repository staff only Download (33kB)

Abstract

The hormone melatonin is increasingly used for the treatment of certain sleep disorders, particularly those related to disturbed biological rhythms. This article summarises current knowledge of its mechanism of action and identifies situations where there is good evidence for its efficacy. The authors provide advice, based on their own experience and consistent published data, concerning the dose range of melatonin to be used and the critically important question of the timing of treatment. Anecdotal evidence for the use of melatonin needs to be replaced by data from well-controlled, preferably multi-centre, randomised clinical trials

Item Type:	Article
Authors :	Name Email ORCID Arendt, J Van Someren, EJW Appleton, R Skene, DJ Akerstedt, T
Date :	1 August 2008
Uncontrolled Keywords :	Science & Technology, Life Sciences & Biomedicine, Medicine, General & Internal, General & Internal Medicine, blindness, children, circadian rhythm, elderly, jet lag, melatonin, neurodisability, shift work, sleep, EXOGENOUS MELATONIN, BRIGHT LIGHT, METAANALYSIS, EFFICACY, SAFETY, BLIND
Related URLs :	Author Publisher
Depositing User :	Symplectic Elements
Date Deposited :	28 Mar 2017 14:09
Last Modified :	31 Oct 2017 14:43
URI:	http://epubs.surrey.ac.uk/id/eprint/721495

Actions (login required)

View Item

Downloads