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Clinical update: melatonin and sleep disorders

Arendt, J, Van Someren, EJW, Appleton, R, Skene, DJ and Akerstedt, T (2008) Clinical update: melatonin and sleep disorders CLINICAL MEDICINE, 8 (4). pp. 381-383.

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Abstract

The hormone melatonin is increasingly used for the treatment of certain sleep disorders, particularly those related to disturbed biological rhythms. This article summarises current knowledge of its mechanism of action and identifies situations where there is good evidence for its efficacy. The authors provide advice, based on their own experience and consistent published data, concerning the dose range of melatonin to be used and the critically important question of the timing of treatment. Anecdotal evidence for the use of melatonin needs to be replaced by data from well-controlled, preferably multi-centre, randomised clinical trials

Item Type: Article
Authors :
AuthorsEmailORCID
Arendt, JUNSPECIFIEDUNSPECIFIED
Van Someren, EJWUNSPECIFIEDUNSPECIFIED
Appleton, RUNSPECIFIEDUNSPECIFIED
Skene, DJUNSPECIFIEDUNSPECIFIED
Akerstedt, TUNSPECIFIEDUNSPECIFIED
Date : 1 August 2008
Uncontrolled Keywords : Science & Technology, Life Sciences & Biomedicine, Medicine, General & Internal, General & Internal Medicine, blindness, children, circadian rhythm, elderly, jet lag, melatonin, neurodisability, shift work, sleep, EXOGENOUS MELATONIN, BRIGHT LIGHT, METAANALYSIS, EFFICACY, SAFETY, BLIND
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 28 Mar 2017 14:09
Last Modified : 28 Mar 2017 14:09
URI: http://epubs.surrey.ac.uk/id/eprint/721495

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