Biophysical characteristics reveal neural stem cell differentiation potential.
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Labeed, FH, Lu, J, Mulhall, HJ, Marchenko, SA, Hoettges, KF, Estrada, LC, Lee, AP, Hughes, MP and Flanagan, LA (2011) Biophysical characteristics reveal neural stem cell differentiation potential. PLoS One, 6 (9). e25458 - ?. ISSN 1932-6203
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Official URL: http://dx.doi.org/10.1371/journal.pone.0025458
Abstract
Distinguishing human neural stem/progenitor cell (huNSPC) populations that will predominantly generate neurons from those that produce glia is currently hampered by a lack of sufficient cell type-specific surface markers predictive of fate potential. This limits investigation of lineage-biased progenitors and their potential use as therapeutic agents. A live-cell biophysical and label-free measure of fate potential would solve this problem by obviating the need for specific cell surface markers.
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Engineering and Physical Sciences > Mechanical Engineering Sciences |
| ID Code: | 712683 |
| Deposited By: | Symplectic Elements |
| Deposited On: | 16 Jul 2012 14:21 |
| Last Modified: | 25 Apr 2013 13:25 |
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