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Biophysical characteristics reveal neural stem cell differentiation potential.

Labeed, FH, Lu, J, Mulhall, HJ, Marchenko, SA, Hoettges, KF, Estrada, LC, Lee, AP, Hughes, MP and Flanagan, LA (2011) Biophysical characteristics reveal neural stem cell differentiation potential. PLoS One, 6 (9). e25458 - ?. ISSN 1932-6203

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Abstract

Distinguishing human neural stem/progenitor cell (huNSPC) populations that will predominantly generate neurons from those that produce glia is currently hampered by a lack of sufficient cell type-specific surface markers predictive of fate potential. This limits investigation of lineage-biased progenitors and their potential use as therapeutic agents. A live-cell biophysical and label-free measure of fate potential would solve this problem by obviating the need for specific cell surface markers.

Item Type: Article
Divisions: Faculty of Engineering and Physical Sciences > Mechanical Engineering Sciences
Depositing User: Symplectic Elements
Date Deposited: 16 Jul 2012 13:21
Last Modified: 23 Sep 2013 19:34
URI: http://epubs.surrey.ac.uk/id/eprint/712683

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