Biophysical characteristics reveal neural stem cell differentiation potential.
Labeed, FH, Lu, J, Mulhall, HJ, Marchenko, SA, Hoettges, KF, Estrada, LC, Lee, AP, Hughes, MP and Flanagan, LA (2011) Biophysical characteristics reveal neural stem cell differentiation potential. PLoS One, 6 (9).
Biophysical Characteristics Reveal Neural Stem Cell Differentiation Potential.pdf
Available under License : See the attached licence file.
Distinguishing human neural stem/progenitor cell (huNSPC) populations that will predominantly generate neurons from those that produce glia is currently hampered by a lack of sufficient cell type-specific surface markers predictive of fate potential. This limits investigation of lineage-biased progenitors and their potential use as therapeutic agents. A live-cell biophysical and label-free measure of fate potential would solve this problem by obviating the need for specific cell surface markers.
|Divisions :||Faculty of Engineering and Physical Sciences > Mechanical Engineering Sciences|
|Identification Number :||https://doi.org/10.1371/journal.pone.0025458|
|Depositing User :||Symplectic Elements|
|Date Deposited :||16 Jul 2012 13:21|
|Last Modified :||23 Sep 2013 19:34|
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