Biophysical characteristics reveal neural stem cell differentiation potential.
Labeed, FH, Lu, J, Mulhall, HJ, Marchenko, SA, Hoettges, KF, Estrada, LC, Lee, AP, Hughes, MP and Flanagan, LA (2011) Biophysical characteristics reveal neural stem cell differentiation potential. PLoS One, 6 (9). e25458 - ?. ISSN 1932-6203
Available under License : See the attached licence file.
Official URL: http://dx.doi.org/10.1371/journal.pone.0025458
Distinguishing human neural stem/progenitor cell (huNSPC) populations that will predominantly generate neurons from those that produce glia is currently hampered by a lack of sufficient cell type-specific surface markers predictive of fate potential. This limits investigation of lineage-biased progenitors and their potential use as therapeutic agents. A live-cell biophysical and label-free measure of fate potential would solve this problem by obviating the need for specific cell surface markers.
|Divisions:||Faculty of Engineering and Physical Sciences > Mechanical Engineering Sciences|
|Deposited By:||Symplectic Elements|
|Deposited On:||16 Jul 2012 14:21|
|Last Modified:||25 Apr 2013 13:25|
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