Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size
Pushparajah, DS, Umachandran, M, Nazir, T, Plant, KE, Plant, N, Lewis, DFV and Ioannides, C (2008) Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size TOXICOLOGY IN VITRO, 22 (1). pp. 128-145.
Pushparajah 2008a CYP1.pdf - Accepted version Manuscript
Available under License : See the attached licence file.
|Divisions :||Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Biochemical Sciences|
|Date :||1 February 2008|
|Identification Number :||10.1016/j.tiv.2007.08.014|
|Uncontrolled Keywords :||Science & Technology, Life Sciences & Biomedicine, Toxicology, TOXICOLOGY, precision-cut slices, polycyclic aromatic hydrocarbons, CYP1A, CYP1B, cytochromes p450, enzyme induction, DNA-ADDUCT FORMATION, CYTOCHROMES P450 1A1, METABOLIC-ACTIVATION, CARCINOGENIC POTENCY, DRUG-METABOLISM, GENE-EXPRESSION, MESSENGER-RNA, C57BL/6J MICE, HEPG2 CELLS, INDUCTION|
|Related URLs :|
|Additional Information :||NOTICE: this is the author’s version of a work that was accepted for publication in Toxicology in Vitro. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Toxicology in Vitro, 22(1), February 2008, DOI 10.1016/j.tiv.2007.08.014.|
|Depositing User :||Symplectic Elements|
|Date Deposited :||09 Mar 2012 17:56|
|Last Modified :||17 Jan 2015 14:52|
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