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Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size

Pushparajah, DS, Umachandran, M, Nazir, T, Plant, KE, Plant, N, Lewis, DFV and Ioannides, C (2008) Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size TOXICOLOGY IN VITRO, 22 (1). 128 - 145. ISSN 0887-2333

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Item Type: Article
Additional Information: NOTICE: this is the author’s version of a work that was accepted for publication in Toxicology in Vitro. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Toxicology in Vitro, 22(1), February 2008, DOI 10.1016/j.tiv.2007.08.014.
Uncontrolled Keywords: Science & Technology, Life Sciences & Biomedicine, Toxicology, precision-cut slices, polycyclic aromatic hydrocarbons, CYP1A, CYP1B, cytochromes p450, enzyme induction, DNA-ADDUCT FORMATION, CYTOCHROMES P450 1A1, METABOLIC-ACTIVATION, CARCINOGENIC POTENCY, DRUG-METABOLISM, GENE-EXPRESSION, MESSENGER-RNA, C57BL/6J MICE, HEPG2 CELLS, INDUCTION
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Divisions: Faculty of Health and Medical Sciences > Biochemistry and Physiology
Depositing User: Symplectic Elements
Date Deposited: 09 Mar 2012 17:56
Last Modified: 23 Sep 2013 19:17
URI: http://epubs.surrey.ac.uk/id/eprint/286639

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