University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Prematurity, Immune Function and Infant Feeding Practices

Hampton, Shelagh M (1999) Prematurity, Immune Function and Infant Feeding Practices Proceedings of the Nutrition Society, 58. pp. 75-78.

prematurity_immune_function_HAMPTON_99.pdf - Version of Record

Download (417kB)


Recently, there has been much interest in the literature in the role of early nutrition and the health of the individual in adulthood. A majority of infants in the UK are born full term, while pretem infants account for 4-6 % of the total births. Milk feeding practices are divided into three groups: breast, combination (breast-fed with formula as ‘top-up’) and bottle (formula). In studies conducted by our group and other researchers immune function in full-term and preterm infants has been assessed by monitoring total and specific immunoglobulin E and specific immunoglobulin G levels. Dietary modification by the pregnant mother with a history of allergy in the family has been shown to have a positive effect with respect to allergy outcome and prevention of atopic disease in the infant. However, this dietary modification has to occur before week 22 of pregnancy and continue until the end of lactation to achieve a beneficial outcome to the infant. The stress of mothers restricting their diets may be disadvantageous to the fetus, and therefore any gain due to the dietary restriction may be lost. Researchers have shown that the early introduction of complementary foods and the greater diversity of these foods appeared to result in an increase in the incidence of atopic disease in the infant. In conclusion, in order to reduce the risk in their babies, mothers with a family history of atopic disease should breast-feed for more than 15 weeks and introduce solid foods after 4 months, limiting the variety until at least 6 months.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Biochemical Sciences
Authors :
Hampton, Shelagh
Date : 1999
DOI : 10.1079/PNS19990011
Related URLs :
Additional Information : Copyright Nutrition Society 1999
Depositing User : Melanie Hughes
Date Deposited : 25 Nov 2010 17:06
Last Modified : 16 Jan 2019 16:25

Actions (login required)

View Item View Item


Downloads per month over past year

Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800