Differential expression of HOX genes upon activation of leukocyte sub-populations
Morgan, R and Whiting, K (2008) Differential expression of HOX genes upon activation of leukocyte sub-populations INTERNATIONAL JOURNAL OF HEMATOLOGY, 87 (3). 246 - 249. ISSN 0925-5710
|PDF - Published Version|
Official URL: http://www.springerlink.com/content/y366814j6u15p6...
The HOX genes are key determinants of cellular identity both in early development and in the renewal and differentiation of adult blood cells. Although a number of studies have examined the expression of individual HOX genes in defined blood cell lineages, we have undertaken a comprehensive analysis of HOX gene expression in resting and activated lymphocytic and monocytic subpopulations. This has revealed distinct patterns of expression between different cell types and resting and activated states. (Main category A: Erythrocytes, Leukocytes and Hematopoiesis, subcategory: 8: Lymphocytes).
|Uncontrolled Keywords:||Science & Technology, Life Sciences & Biomedicine, Hematology, HOX, T-lymphocytes, B-lymphocytes, monocytes, activation, LINEAGE COMMITMENT, HOMEOBOX GENES, HEMATOPOIESIS, CELLS|
|Divisions:||Faculty of Health and Medical Sciences > Microbial and Cellular Sciences|
|Deposited By:||Melanie Hughes|
|Deposited On:||05 Nov 2010 11:04|
|Last Modified:||16 Feb 2013 16:52|
Repository Staff Only: item control page