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Differential expression of HOX genes upon activation of leukocyte sub-populations

Morgan, R and Whiting, K (2008) Differential expression of HOX genes upon activation of leukocyte sub-populations INTERNATIONAL JOURNAL OF HEMATOLOGY, 87 (3). 246 - 249. ISSN 0925-5710

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Abstract

The HOX genes are key determinants of cellular identity both in early development and in the renewal and differentiation of adult blood cells. Although a number of studies have examined the expression of individual HOX genes in defined blood cell lineages, we have undertaken a comprehensive analysis of HOX gene expression in resting and activated lymphocytic and monocytic subpopulations. This has revealed distinct patterns of expression between different cell types and resting and activated states. (Main category A: Erythrocytes, Leukocytes and Hematopoiesis, subcategory: 8: Lymphocytes).

Item Type: Article
Uncontrolled Keywords: Science & Technology, Life Sciences & Biomedicine, Hematology, HOX, T-lymphocytes, B-lymphocytes, monocytes, activation, LINEAGE COMMITMENT, HOMEOBOX GENES, HEMATOPOIESIS, CELLS
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Divisions: Faculty of Health and Medical Sciences > Microbial and Cellular Sciences
Depositing User: Melanie Hughes
Date Deposited: 05 Nov 2010 11:04
Last Modified: 23 Sep 2013 18:39
URI: http://epubs.surrey.ac.uk/id/eprint/2593

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