University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Digital Autoradiography using CCD and CMOS Imaging Technology

Cabello, J, Bailey, A, Kitchen, I, Clark, A, Crooks, J, Halsall, R, Key-Charriere, M, Martin, S, Prydderch, M, Turchetta, R and Wells, K (2006) Digital Autoradiography using CCD and CMOS Imaging Technology 2006 IEEE Nuclear Science Symposium Conference Record, 4. pp. 2607-2612. ISSN 1082-3654

[img]
Preview
PDF
digital_autoradiography_CABELLO_06.pdf - Published Version

Download (912kB)

Abstract

CCD and CMOS imaging technologies can be applied to thin tissue Autoradiography as potential imaging alternatives to using conventional film. In this work, we compare two particular devices; a CCD operating in slow scan mode and a CMOS-based Active Pixel sensor, operating at near video rates. Both imaging sensors have been operated at room temperature with images produced from calibrated microscales and radiolabelled tissue samples. We also compare these digital imaging technologies with the use of conventional film. We show first comparative results obtained with 14C calibrated microscales and 35S radiolabelled tissue sections. We also present first results of 3H images produced under direct irradiation of a CCD sensor operating at room temperature. Compared to film, silicon-based imaging technologies exhibit enhanced sensitivity, dynamic range and linearity.

Item Type: Article
Additional Information: ©2006 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
Related URLs:
Divisions: Faculty of Health and Medical Sciences > Biochemistry and Physiology
Depositing User: Melanie Hughes
Date Deposited: 03 Nov 2010 09:38
Last Modified: 23 Sep 2013 18:39
URI: http://epubs.surrey.ac.uk/id/eprint/2581

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year


Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800