Differential effects of long-chain fatty acids and clofibrate on gene expression profiles in cardiomyocytes.
Khodadadi, I, Griffin, B and Thumser, A (2008) Differential effects of long-chain fatty acids and clofibrate on gene expression profiles in cardiomyocytes. Arch Iran Med, 11 (1). 42 - 49. ISSN 1029-2977
The link between dietary fat and coronary heart disease has attracted much attention since the effect of long-chain fatty acids on gene transcription has been established. The aim of this study was to investigate the effects of long-chain fatty acids and clofibrate on mRNA levels of specific lipid metabolism-related genes and to determine their effects on global transcriptome levels in a cardiovascular cell-line.
|Divisions :||Faculty of Health and Medical Sciences > Biochemistry and Physiology|
|Date :||January 2008|
|Uncontrolled Keywords :||Analysis of Variance, Cells, Cultured, Clofibrate, Fatty Acids, Gene Expression Regulation, Myocytes, Cardiac, Reverse Transcriptase Polymerase Chain Reaction, Transcription Factors|
|Depositing User :||Mr Adam Field|
|Date Deposited :||27 May 2010 14:46|
|Last Modified :||09 Jun 2014 13:26|
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