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Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa).

Agouni, A, Lagrue-Lak-Hal, AH, Mostefai, HA, Tesse, A, Mulder, P, Rouet, P, Desmoulin, F, Heymes, C, Martínez, MC and Andriantsitohaina, R (2009) Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa). PLoS One, 4 (5). e5557 - ?. ISSN 1932-6203

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Official URL: http://dx.doi.org/10.1371/journal.pone.0005557

Abstract

Obesity is associated with increased risks for development of cardiovascular diseases. Epidemiological studies report an inverse association between dietary flavonoid consumption and mortality from cardiovascular diseases. We studied the potential beneficial effects of dietary supplementation of red wine polyphenol extract, Provinols, on obesity-associated alterations with respect to metabolic disturbances and cardiovascular functions in Zucker fatty (ZF) rats.

Item Type:Article
Additional Information:© 2009 Agouni et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Uncontrolled Keywords:Animals, Blood Glucose, Blood Pressure, Blotting, Western, Echocardiography, Electron Spin Resonance Spectroscopy, Enzyme Activation, Flavonoids, Fructosamine, Lipid Metabolism, Lipids, Mesenteric Arteries, NADPH Oxidase, Nitric Oxide, Nitric Oxide Synthase Type III, Obesity, Phenols, Rats, Rats, Zucker, Superoxides, Wine
Divisions:Faculty of Health and Medical Sciences > Biochemistry and Physiology
ID Code:158132
Deposited By:Symplectic Elements
Deposited On:25 Jan 2012 08:42
Last Modified:28 Apr 2013 14:38

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