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Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa).

Agouni, A, Lagrue-Lak-Hal, AH, Mostefai, HA, Tesse, A, Mulder, P, Rouet, P, Desmoulin, F, Heymes, C, Martínez, MC and Andriantsitohaina, R (2009) Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa). PLoS One, 4 (5).

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Abstract

Obesity is associated with increased risks for development of cardiovascular diseases. Epidemiological studies report an inverse association between dietary flavonoid consumption and mortality from cardiovascular diseases. We studied the potential beneficial effects of dietary supplementation of red wine polyphenol extract, Provinols, on obesity-associated alterations with respect to metabolic disturbances and cardiovascular functions in Zucker fatty (ZF) rats.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Biochemical Sciences
Authors :
AuthorsEmailORCID
Agouni, AUNSPECIFIEDUNSPECIFIED
Lagrue-Lak-Hal, AHUNSPECIFIEDUNSPECIFIED
Mostefai, HAUNSPECIFIEDUNSPECIFIED
Tesse, AUNSPECIFIEDUNSPECIFIED
Mulder, PUNSPECIFIEDUNSPECIFIED
Rouet, PUNSPECIFIEDUNSPECIFIED
Desmoulin, FUNSPECIFIEDUNSPECIFIED
Heymes, CUNSPECIFIEDUNSPECIFIED
Martínez, MCUNSPECIFIEDUNSPECIFIED
Andriantsitohaina, RUNSPECIFIEDUNSPECIFIED
Date : 2009
Identification Number : 10.1371/journal.pone.0005557
Uncontrolled Keywords : Animals, Blood Glucose, Blood Pressure, Blotting, Western, Echocardiography, Electron Spin Resonance Spectroscopy, Enzyme Activation, Flavonoids, Fructosamine, Lipid Metabolism, Lipids, Mesenteric Arteries, NADPH Oxidase, Nitric Oxide, Nitric Oxide Synthase Type III, Obesity, Phenols, Rats, Rats, Zucker, Superoxides, Wine
Additional Information : © 2009 Agouni et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Depositing User : Symplectic Elements
Date Deposited : 25 Jan 2012 08:42
Last Modified : 23 Sep 2013 19:04
URI: http://epubs.surrey.ac.uk/id/eprint/158132

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